ID I4MCR6_GARVA Unreviewed; 580 AA.
AC I4MCR6;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=CGSMWGv6119V5_05056 {ECO:0000313|EMBL:EIK87006.1};
OS Gardnerella vaginalis 6119V5.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Gardnerella.
OX NCBI_TaxID=698961 {ECO:0000313|EMBL:EIK87006.1, ECO:0000313|Proteomes:UP000033041};
RN [1] {ECO:0000313|EMBL:EIK87006.1, ECO:0000313|Proteomes:UP000033041}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6119V5 {ECO:0000313|EMBL:EIK87006.1,
RC ECO:0000313|Proteomes:UP000033041};
RX PubMed=22609915; DOI=10.1128/JB.00056-12;
RA Ahmed A., Earl J., Retchless A., Hillier S., Rabe L., Cherpes T.,
RA Powell E., Janto B., Eutsey R., Hiller N.L., Boissy R., Dahlgreen M.,
RA Hall B., Costerton J., Post J.C., Hu F., Ehrlich G.;
RT "Comparative Genomic Analyses of 17 Clinical Isolates of Gardnerella
RT vaginalis Provide Evidence of Multiple Genetically Isolated Clades
RT Consistent with Subspeciation into Genovars.";
RL J. Bacteriol. 194:3922-3937(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIK87006.1}.
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DR EMBL; ADEW01000011; EIK87006.1; -; Genomic_DNA.
DR RefSeq; WP_004137276.1; NZ_ADEW01000011.1.
DR AlphaFoldDB; I4MCR6; -.
DR PATRIC; fig|698961.3.peg.1000; -.
DR eggNOG; COG2815; Bacteria.
DR OrthoDB; 3240505at2; -.
DR Proteomes; UP000033041; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06577; PASTA_pknB; 2.
DR Gene3D; 3.30.10.20; -; 1.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR026870; Zinc_ribbon_dom.
DR Pfam; PF03793; PASTA; 1.
DR Pfam; PF13240; zinc_ribbon_2; 1.
DR PROSITE; PS51178; PASTA; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EIK87006.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:EIK87006.1};
KW Transferase {ECO:0000313|EMBL:EIK87006.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 80..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 246..308
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 580 AA; 63268 MW; A1C1BE8485A36C6C CRC64;
MAFCVNCGSK LDEGSKFCSS CGSSVENYSE SKNYATSANY GSQLTENPTI ANSGINSDAV
NCAVKNNNLQ GFFNSKQGKI VIAAIASVVV VAIMIFCWLQ FDAHSNRNIS IPKASALKSV
PLQKTVDNLR KQGLNVTVSK EFSSVKRGGF VRFANVHPGQ SVPSSSHITV IESNGPGIPK
KGVVGQSIEK AKKVANSMGV PVEVYNIIST NTGKVVATDP MPGFPVSNGS SDKSVIRLAV
GVEGKGVPAD LFGMDKDEAV NKLRDLGLKD VSLHPHFSSE KNLGKIIASN PALGTKFSGG
HIDLYYGVDA SETKNIMTMN SPDDNSVRWA TNTAPAMFGT WCTNDGDCME LQTHYYPKTN
PIFTFLQFPD DPVDSNDSRF YEYLALCNYS QDPGACTLPH DYESGREDRM KNHLLSGDTG
AFELYRGMGL PYCGETTNDN IGNICVNGKW VDSFEPPEDI KQYGSPDKIP GYWKGSSFRM
RDFFLVVPVH ANLNKIESSG YFEGKGNKKP DTTRPFILRR NPKLYTQTTV DAEPYKGDIG
DNPFVPTNKH KAAPFKPAPD DSVAYYLVEK PFDWSKLPIA
//
