ID I4ZCB2_9BACT Unreviewed; 444 AA.
AC I4ZCB2;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:EIM33854.1};
GN ORFNames=PrebiDRAFT_2203 {ECO:0000313|EMBL:EIM33854.1};
OS Prevotella bivia DSM 20514.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=868129 {ECO:0000313|EMBL:EIM33854.1, ECO:0000313|Proteomes:UP000002786};
RN [1] {ECO:0000313|EMBL:EIM33854.1, ECO:0000313|Proteomes:UP000002786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20514 {ECO:0000313|EMBL:EIM33854.1,
RC ECO:0000313|Proteomes:UP000002786};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Munk A.C.C., Kyrpides N., Mavromatis K.,
RA Detter J.C., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "Improved High-Quality Draft genome of Prevotella bivia DSM 20514.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; JH660658; EIM33854.1; -; Genomic_DNA.
DR RefSeq; WP_004338886.1; NZ_JH660658.1.
DR AlphaFoldDB; I4ZCB2; -.
DR GeneID; 78529688; -.
DR HOGENOM; CLU_018816_2_1_10; -.
DR Proteomes; UP000002786; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF23; MULTIDRUG RESISTANCE PROTEIN MEXA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002786};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..444
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003698891"
FT DOMAIN 59..103
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT REGION 425..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 157..205
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 444 AA; 46726 MW; C1279B93BF308725 CRC64;
MKANKFLVVA AVAATVFVSC GKGQQTLPTS DEFPVMTIGS SSAQSKSTYP ATIKGIQDVE
VRPKVSGFIT HLNVHEGQYV KAGQVLFVID NSTYQEAVRQ GQAHVDAAQS AVAQARAAVN
TANASLNSAK AQEATARLTY SNSKNLYANK VIGDYELQAA KNTYATAEAA VRQAQSGVAQ
ATAAIQQAEA GVKQAQAGLA TAKENLGFCY VKSPTSGYIG SLPYKEGALV SPSSAQPVTT
VSNISTMEVY FSLTEADMLK LSRSSNGLAS AIQKFPSVSL QLIDGSIYSH EGTVVKTSGI
VDAATGTISV IARFPNPEKL LKSGGSGQII IAKSNNHAMV IPQDAVVQVQ DKMFVYKVDQ
DNKVHYTEIT VSPENDGNNY VVTSGLKMGD KIVTKGVSTL TDGAKIKALT EAEYAKAIEK
AEELSKNQNS ASGFVEAMQG GDKK
//
