ID I5C4B3_9BACT Unreviewed; 514 AA.
AC I5C4B3;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=aldehyde dehydrogenase (NAD(+)) {ECO:0000256|ARBA:ARBA00024226};
DE EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN ORFNames=A3SI_09423 {ECO:0000313|EMBL:EIM76665.1};
OS Nitritalea halalkaliphila LW7.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Nitritalea.
OX NCBI_TaxID=1189621 {ECO:0000313|EMBL:EIM76665.1, ECO:0000313|Proteomes:UP000005551};
RN [1] {ECO:0000313|EMBL:EIM76665.1, ECO:0000313|Proteomes:UP000005551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LW7 {ECO:0000313|EMBL:EIM76665.1,
RC ECO:0000313|Proteomes:UP000005551};
RA Jangir P.K., Singh A., Shivaji S., Sharma R.;
RT "Genome sequence of Nitritalea halalkaliphila LW7.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIM76665.1}.
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DR EMBL; AJYA01000019; EIM76665.1; -; Genomic_DNA.
DR RefSeq; WP_009054852.1; NZ_AJYA01000019.1.
DR AlphaFoldDB; I5C4B3; -.
DR STRING; 1189621.A3SI_09423; -.
DR PATRIC; fig|1189621.3.peg.1962; -.
DR OrthoDB; 973869at2; -.
DR Proteomes; UP000005551; Unassembled WGS sequence.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR CDD; cd07130; ALDH_F7_AASADH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR044638; ALDH7A1-like.
DR PANTHER; PTHR43521; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43521:SF1; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000005551}.
FT DOMAIN 29..495
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 267
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 514 AA; 55719 MW; 52E1ABAD5BABB0F3 CRC64;
MDSKNKMQAV LERLGIQAEN SGTSTGSEWV TSTGDYFSSI SPVDGEAIAA VQATDAAAYA
RVMERATAAF KEWRTVPAPQ RGEVVRQIGD ALRAHKEDLG TLVSYEMGKS YQEGLGEVQE
MIDICDFAVG LSRQLYGLTM HSERPAHRMY EQYHPLGVVG IISAFNFPVA VWSWNTMLAW
VCGDVCVWKP SEKAPLSALA CQHIVAPIFA RNGYPEGISC LIQGDYRVGE WLSQDKRIPL
VSATGSTRMG KIVAATVAER LGRSLLELGG NNAIIISPEA DMEIAIRGAL FGAVGTAGQR
CTTTRRLIVH SSVYEQVKER LVAAYGKLNI GNPLDEKHHV GPLIDKEAVS AYLKTIDAVQ
QEGGRVLIPA RVLEGPGFES GCYVQPTIVE AENHYQKVQE ETFAPILYLL RYETLEEAIE
MQNAVPQGLS SAIMTLNMRE AEQFLSAAGS DCGIANVNIG TSGAEIGGAF GGEKETGGGR
ESGSDAWKVY MRRQTNTINY STALPLAQGI KFDI
//
