ID I5C635_9BACT Unreviewed; 429 AA.
AC I5C635;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 13-SEP-2023, entry version 33.
DE SubName: Full=Nucleotide sugar dehydrogenase {ECO:0000313|EMBL:EIM77287.1};
GN ORFNames=A3SI_06869 {ECO:0000313|EMBL:EIM77287.1};
OS Nitritalea halalkaliphila LW7.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Nitritalea.
OX NCBI_TaxID=1189621 {ECO:0000313|EMBL:EIM77287.1, ECO:0000313|Proteomes:UP000005551};
RN [1] {ECO:0000313|EMBL:EIM77287.1, ECO:0000313|Proteomes:UP000005551}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LW7 {ECO:0000313|EMBL:EIM77287.1,
RC ECO:0000313|Proteomes:UP000005551};
RA Jangir P.K., Singh A., Shivaji S., Sharma R.;
RT "Genome sequence of Nitritalea halalkaliphila LW7.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIM77287.1}.
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DR EMBL; AJYA01000015; EIM77287.1; -; Genomic_DNA.
DR RefSeq; WP_009054218.1; NZ_AJYA01000015.1.
DR AlphaFoldDB; I5C635; -.
DR STRING; 1189621.A3SI_06869; -.
DR PATRIC; fig|1189621.3.peg.1431; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000005551; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000005551}.
FT DOMAIN 326..422
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 429 AA; 47385 MW; FFD41EDE0D8A156A CRC64;
MELQLNEVKI GIIGLGYVGL PLAVAFAEKY PTIGLDINPK RIQELRAGLD TTLEVEDADL
QQVLLQAPGA KGLFVSDAPE DLADCQVYVV TVPTPTDKHN RPVLTPMIKA SETVGKLLKK
GDVVIYESTV YPGVTEDECV PILEAISGMK FNTDFYVGYS PERINPGDKL HTVTKILKVT
SGSTPEAADF VDALYKSVIT AGTFKASCIK VAEAAKVIEN SQRDINIAFV NELSKIFNLL
DIDTYEVLEA AGTKWNFLPF RPGLVGGHCI GVDPYYLAQK AQEVGYHPEI ILAGRRLNDS
MGKHVATEVI KKMMHKNLPV LQAKVLLLGF TFKENCPDVR NTRVIDIYEE LRRFDMQVDV
YDPLASSEEV ADEYGLKLLT EKPDLSAYAA IILAVAHKEF EQLDLSTSPD RVIYDVKAVL
PKERVDARL
//
