ID I5CCI4_9BURK Unreviewed; 983 AA.
AC I5CCI4;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Molybdopterin oxidoreductase {ECO:0000313|EMBL:EIM93602.1};
GN ORFNames=WQE_48398 {ECO:0000313|EMBL:EIM93602.1};
OS Paraburkholderia hospita BS001.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=1171375 {ECO:0000313|EMBL:EIM93602.1};
RN [1] {ECO:0000313|EMBL:EIM93602.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BS001 {ECO:0000313|EMBL:EIM93602.1};
RX PubMed=22843604; DOI=10.1128/JB.00725-12;
RA Nazir R., Hansen M.A., Sorensen S., van Elsas J.D.;
RT "Draft Genome Sequence of the Soil Bacterium Burkholderia terrae Strain
RT BS001, Which Interacts with Fungal Surface Structures.";
RL J. Bacteriol. 194:4480-4481(2012).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIM93602.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKAU01000302; EIM93602.1; -; Genomic_DNA.
DR AlphaFoldDB; I5CCI4; -.
DR PATRIC; fig|1171375.3.peg.9982; -.
DR Proteomes; UP000004980; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02783; MopB_CT_2; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.30.200.210; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43598:SF5; DMSO REDUCTASE CHAIN A; 1.
DR PANTHER; PTHR43598; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 12..68
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
FT REGION 430..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..452
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 983 AA; 110076 MW; E9FA1064C346290B CRC64;
MEHKARTQNE KLEVKTTTCY MCACRCGIRV HLRDGEVRYI DGNPDHPLNQ GVICAKGSSG
IMKQYSPARL TQPLMRKPDA LRGTAQFEPV SWELAFDVLE KRLAHIRATD PKKFALFTGR
DQMQALTGLF ARQFGTPNYA AHGGFCSVNM AAGMIYTMGG SFWEFGGPDL DRAKLFFMIG
TAEDHHSNPL KIAISKFKRA GGRFIAINPV RTGYAAIADE WVPIRPGTDG ALFMALMREL
IESNAYDREF VERYTNAGEL LDIREDSDTQ GLFVCDEDAQ ACNAMFPQNH LWWDPVSQRE
VLHHTPGVRP ALEGRYALAD GTPVAPSFVL LREQLADCTP DWASGITGIP VDTIRRLARE
MADVSRDQKI TLPIQWTDAW GETHETVTGA PIAFHAMRGL AGHSNGFQTI RALAVLMSLL
GTIDRPGGFR HKSPYPRAVP PSAKPPNSPD DVKPNTPLAN GPLGWPAGPE DLFIHDSGEP
VRIDKAFSWE YPLAVHGLMH SVITNAWRGD PYPIDTLLIF MANLAWNSSM NTVEVRKMLV
DRNEDGEYKI PFIVVCDAFQ SEMTAFADLI LPDTTYLERY DAMSMLDRPI SEFDGPVDSV
RVPVVPATGE CKPFQEVLVE LASRLKFPAF TTPDGKRKYR DYPEFIVNHQ TAPGSGVGFL
IGWRGKDGKD VLVGEPNPKQ WEEYAKHNCV YHYTLPETLQ YMRNCNGPYL DFAVEKGFRK
FNTPIVIALY SDVMQKFRLA AQGKTKGRQP PEHLRARIAR YFDPLPSWYP PLEHGTTDHA
RFPLAAITQR PMAMYHSWDS QNAWLRQIHG ENYLYMNPRT AAAQGIEDGG WIYVESQWGK
VRCIARYSEA VEPGTVWTWN AIGKSAGAWN LGPDANESQR GFLLNHLITD EIPVDDLRHV
RTSNSDPVTG QAAWYDVRVR IYPAEADADH TLPQFAPMPA SMPGMVGTES GGMIHRIVQT
YFAGRGEFAA RLKAVQRKTT QRN
//
