ID I6AUH4_9BACT Unreviewed; 435 AA.
AC I6AUH4;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Uracil-xanthine permease {ECO:0000313|EMBL:EIP98665.1};
GN ORFNames=OpiT1DRAFT_03128 {ECO:0000313|EMBL:EIP98665.1};
OS Opitutaceae bacterium TAV1.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX NCBI_TaxID=278956 {ECO:0000313|EMBL:EIP98665.1, ECO:0000313|Proteomes:UP000004921};
RN [1] {ECO:0000313|EMBL:EIP98665.1, ECO:0000313|Proteomes:UP000004921}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TAV1 {ECO:0000313|EMBL:EIP98665.1,
RC ECO:0000313|Proteomes:UP000004921};
RX PubMed=22535930; DOI=10.1128/JB.00264-12;
RA Isanapong J., Goodwin L., Bruce D., Chen A., Detter C., Han J., Han C.S.,
RA Held B., Huntemann M., Ivanova N., Land M.L., Mavromatis K., Nolan M.,
RA Pati A., Pennacchio L., Pitluck S., Szeto E., Tapia R., Woyke T.,
RA Rodrigues J.L.;
RT "High-Quality Draft Genome Sequence of the Opitutaceae Bacterium Strain
RT TAV1, a Symbiont of the Wood-Feeding Termite Reticulitermes flavipes.";
RL J. Bacteriol. 194:2744-2745(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH660698; EIP98665.1; -; Genomic_DNA.
DR AlphaFoldDB; I6AUH4; -.
DR HOGENOM; CLU_017959_1_2_0; -.
DR Proteomes; UP000004921; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 435 AA; 44989 MW; CEE73D3AFAA6EEC1 CRC64;
MKPRAAASSS PAPSATDYTF RFGDALVGAQ MLFVAFGALV LVPILTGLNP NVALFTAGLG
TLIYQLITKG KVPVFVASSF AFIAPIQYGL GKDGWGLPAT LCGLVGAGFI YFVVSMLIRW
RGIGFIRKII PAVVVGPVVM VIGLLLAPVA ADMAMGRTSG GAIPQWQALV IAGISLLAMV
LVSLLGRGML RLLPILCGIA AGYVASLAMG FVNFEKVIAA PWIAMPAFVT PTWNLSAILF
IAPVALAPII EHYGAIQAIG QITGRDYVKN PGIDRCLFGD GVATSVAGML GGPPCTTYSE
VIGAVALTRA FNPAIMTWAA ITAILLAFVG KVGAVLATIP GPVMGGIMTL LFGAIAVVGM
QTLARSREDL LEPRNMTIVA LVLVCGIGGM VIGDKQSFAL EGIGLAGILG IVLNLVLPKA
RPETAVMEAG EKTRE
//
