ID I6L1R8_BOVIN Unreviewed; 643 AA.
AC I6L1R8;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Tigger transposable element derived 5 {ECO:0000313|Ensembl:ENSBTAP00000054451.2};
GN Name=TIGD5 {ECO:0000313|Ensembl:ENSBTAP00000054451.2,
GN ECO:0000313|VGNC:VGNC:35867};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000054451.2, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000054451.2, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000054451.2,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000054451.2}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000054451.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00320}.
CC -!- SIMILARITY: Belongs to the tigger transposable element derived protein
CC family. {ECO:0000256|ARBA:ARBA00010881}.
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DR AlphaFoldDB; I6L1R8; -.
DR SMR; I6L1R8; -.
DR Ensembl; ENSBTAT00000066224.2; ENSBTAP00000054451.2; ENSBTAG00000048160.2.
DR VEuPathDB; HostDB:ENSBTAG00000048160; -.
DR VGNC; VGNC:35867; TIGD5.
DR GeneTree; ENSGT00940000154420; -.
DR HOGENOM; CLU_018294_1_1_1; -.
DR InParanoid; I6L1R8; -.
DR OMA; AYKCLAP; -.
DR OrthoDB; 3535964at2759; -.
DR TreeFam; TF338616; -.
DR Proteomes; UP000009136; Chromosome 14.
DR Bgee; ENSBTAG00000048160; Expressed in longissimus thoracis muscle and 105 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR19303:SF56; TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 5; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03184; DDE_1; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 52..103
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 117..190
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 79..99
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..49
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..387
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 643 AA; 70317 MW; 562E9A36CCB4FCCE CRC64;
MYSAGPPAVP APRRCRRPPP GRPMQPPRPP APAPVPAARP PPPAPGPRPR VAVKMAFRKA
YSIKDKLQAI ERVKGGERQA SVCRDFGVPG GTLRGWLKDE PKLRWFLEQL GGEVGTQRKK
MRLANEEEID RAVYSWFLAL RQHGVPLSGP LIQAQAEAFA RQIYGPECTF KASHGWFWRW
QKRHGISSQR IYGEAEPVAA GPAPGPPVNQ EPAQPTRAGP LPDRAASTPA PAEGGYGDEQ
IYNANVTGLY WKLLPEQAAP VGAGGCGRRW RGDRVTVLLA ANLTGSHKLK PLVIGQLPDP
PSLRHHNQDK FPASYRYSPD AWLSRPLLRG WFFEEFVPGV RRYLRRSCLQ QKAVLLVAHP
PCPSSEARMP ALEESEETRR RCRPEPTGPP EELQTPDGAV RVLFLCRGSG RAHIPAPLEQ
GVVAAFKQLY KRELLRLAVS CAGGSPLDFM RSFMLKDMLY LAGLSWDLVQ AGSIERCWLL
GLRAAFEPRP VEERAGQPAG QAEEAAEHSR VLSDLTHLAA LAYKRLAPEE VAEWLHLDDD
GGLPDGGRED WGPSRPPVLV PGGPLLPASL PSAVAGGAEE EEEEAIPTAG EAVRGLETAL
RWLETQDPRE VGPLKLVQLR SLISTARRLG GIGPSPMVPD DGL
//
