ID I6T470_GYMAC Unreviewed; 289 AA.
AC I6T470;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Polycystic kidney disease 1 {ECO:0000313|EMBL:AFM80378.1};
DE Flags: Fragment;
OS Gymnodraco acuticeps (Antarctic dragonfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Notothenioidei; Bathydraconidae; Gymnodraco.
OX NCBI_TaxID=8218 {ECO:0000313|EMBL:AFM80378.1};
RN [1] {ECO:0000313|EMBL:AFM80378.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TA255GYVI1 {ECO:0000313|EMBL:AFM80378.1};
RA Dettai A., Berkani M., Lautredou A.C., Couloux A., Lecointre G.,
RA Ozouf-Costaz C., Gallut C.;
RT "Tracking the elusive monophyly of nototheniid fishes (Teleostei) with
RT multiple mitochondrial and nuclear markers.";
RL Mar. Genomics 0:0-0(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JQ688759; AFM80378.1; -; Genomic_DNA.
DR AlphaFoldDB; I6T470; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR46730; POLYCYSTIN-1; 1.
DR PANTHER; PTHR46730:SF3; POLYCYSTIN-1; 1.
DR Pfam; PF00801; PKD; 2.
DR Pfam; PF18911; PKD_4; 1.
DR SMART; SM00089; PKD; 3.
DR SUPFAM; SSF49299; PKD domain; 3.
DR PROSITE; PS50093; PKD; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 19..89
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 110..156
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 185..243
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFM80378.1"
FT NON_TER 289
FT /evidence="ECO:0000313|EMBL:AFM80378.1"
SQ SEQUENCE 289 AA; 31894 MW; 48724806830A29B8 CRC64;
ILTRVDIQTE PQLLLTDKSA EFEAHPLPSP YGIHYDWRFG DGSPPMQGRR VAHTYAQSGI
FNVCVSVNNT ISSMEACAEV FVFEEIDDLT AKSSSPTELH SPTVVQARLG SGNNITWTFS
MGDGEMYTTS TPHMSHKYVT EGNYTVNVTA ANAVSSGWTL VAVQVFVFQV VRMEPSGCVQ
ERTLVNFQAW VSGNASAHLY EWSFGDGSPN ETHQGNPTVS HTYWTSGKYH LSLRLSSGVN
KATKANFFNW VCVQPALTNI SLSLDKSHYA VGEKISFQAR AQPESNYSY
//
