ID   I6ZIQ1_MYCWM            Unreviewed;       459 AA.
AC   I6ZIQ1;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Multifunctional aminopeptidase A {ECO:0000313|EMBL:AFN65070.1};
DE            EC=3.4.11.1 {ECO:0000313|EMBL:AFN65070.1};
GN   OrderedLocusNames=WEN_01355 {ECO:0000313|EMBL:AFN65070.1};
OS   Mycoplasma wenyonii (strain Massachusetts) (Eperythrozoon wenyonii).
OC   Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=1197325 {ECO:0000313|EMBL:AFN65070.1, ECO:0000313|Proteomes:UP000009005};
RN   [1] {ECO:0000313|EMBL:AFN65070.1, ECO:0000313|Proteomes:UP000009005}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Massachusetts {ECO:0000313|EMBL:AFN65070.1,
RC   ECO:0000313|Proteomes:UP000009005};
RX   PubMed=22965086; DOI=10.1128/JB.01240-12;
RA   Dos Santos A.P., Guimaraes A.M., do Nascimento N.C., Sanmiguel P.J.,
RA   Messick J.B.;
RT   "Complete genome sequence of Mycoplasma wenyonii strain Massachusetts.";
RL   J. Bacteriol. 194:5458-5459(2012).
CC   -!- SIMILARITY: Belongs to the peptidase M17 family.
CC       {ECO:0000256|ARBA:ARBA00009528}.
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DR   EMBL; CP003703; AFN65070.1; -; Genomic_DNA.
DR   RefSeq; WP_014849780.1; NC_018149.1.
DR   AlphaFoldDB; I6ZIQ1; -.
DR   STRING; 1197325.WEN_01355; -.
DR   KEGG; mwe:WEN_01355; -.
DR   PATRIC; fig|1197325.3.peg.293; -.
DR   HOGENOM; CLU_013734_6_3_14; -.
DR   Proteomes; UP000009005; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR011356; Leucine_aapep/pepB.
DR   InterPro; IPR000819; Peptidase_M17_C.
DR   PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR   PANTHER; PTHR11963:SF23; ZGC:152830; 1.
DR   Pfam; PF00883; Peptidase_M17; 1.
DR   PRINTS; PR00481; LAMNOPPTDASE.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR   PROSITE; PS00631; CYTOSOL_AP; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW   ECO:0000313|EMBL:AFN65070.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AFN65070.1};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009005}.
FT   DOMAIN          306..313
FT                   /note="Cytosol aminopeptidase"
FT                   /evidence="ECO:0000259|PROSITE:PS00631"
SQ   SEQUENCE   459 AA;  51284 MW;  0153D1C69B8D2A48 CRC64;
     MVVQPKKDTR VFRLVASKII DCEIKHLDYR IDYENASAQF FVDPKKVKTK EFLPALRGCL
     ESAYSWDIDY LSFVEATKTG LKSFELELCL RGLIDSILRT PKKYLHAKKQ KPKKTCRQIQ
     LIGLKSASKE ITNILSCENQ IKDWSELPPN ILDAEKFVAE IISCSRELNI DYEVLNWDEL
     NLKGFNLTCA VGQNKRNSYL VTLRESKERR EKKKDRKRIV IIGKGICFDT GGLSIKTGGN
     MVGMKFDMTG AGLVAAIFFA LAKNKFSDKH EVIAVLPISE NLIGSDSIKV DSVIQSYGGK
     FIEISNTDAE GRLLLAEAIS YAAKDLEASE IITVATLTGA VGYALGKKYA GAWSSSEENW
     KRFNFLADYT GEHVWRLPLD KYYLEKLKSS IAELKNSATT GVGGASRAAT FLAEFRDNKD
     FIHLDIANVS SSSGNSCVAL APLFKTIYFY LKGERSSVK
//