ID   I6ZYZ3_9REOV            Unreviewed;       132 AA.
AC   I6ZYZ3;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=NSP4 {ECO:0000313|EMBL:AFN71030.1};
DE   Flags: Fragment;
OS   Rotavirus A.
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Sedoreoviridae; Rotavirus.
OX   NCBI_TaxID=28875 {ECO:0000313|EMBL:AFN71030.1};
RN   [1] {ECO:0000313|EMBL:AFN71030.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=RVA/Cow-wt/TUR/Bursa/2000/G10P5 {ECO:0000313|EMBL:AFN71030.1};
RA   Timurkan M.O., Alkan F.;
RT   "Molecular characterization of VP4, VP6, VP7 and NSP4 genes of group A
RT   rotavirus strains in different species in Turkey.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; JQ956388; AFN71030.1; -; Genomic_RNA.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.430; -; 1.
DR   InterPro; IPR002107; Rotavirus_NSP4.
DR   Pfam; PF01452; Rota_NSP4; 1.
DR   SUPFAM; SSF58030; Rotavirus nonstructural proteins; 1.
PE   4: Predicted;
KW   Activation of host autophagy by virus {ECO:0000256|ARBA:ARBA00023050};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Enterotoxin {ECO:0000256|ARBA:ARBA00022861};
KW   Host-virus interaction {ECO:0000256|ARBA:ARBA00023050};
KW   Membrane {ECO:0000256|SAM:Phobius}; Toxin {ECO:0000256|ARBA:ARBA00022656};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        13..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   COILED          69..96
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AFN71030.1"
FT   NON_TER         132
FT                   /evidence="ECO:0000313|EMBL:AFN71030.1"
SQ   SEQUENCE   132 AA;  15645 MW;  A347CB1862BC4869 CRC64;
     MNSTLHTILE DPGMAYFPYI ASVLTILFTL HKASIPTMKM ALKTSKCSYK VVKYCIVTIF
     NTLFKLAGYK EQITTKDEIE KQMDRVVKEM RRQLKMIDKL TTREIEQVEL LKRIYEKLRM
     RTADERYTTK YT
//