ID I7FIH1_GEOSL Unreviewed; 135 AA.
AC I7FIH1;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Sodium/proton antiporter complex Mrp, protein B {ECO:0000313|EMBL:AFP20468.1};
GN Name=mrpB {ECO:0000313|EMBL:AFP20468.1};
GN OrderedLocusNames=GSU2343 {ECO:0000313|EMBL:AFP20468.1};
OS Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=243231 {ECO:0000313|EMBL:AFP20468.1, ECO:0000313|Proteomes:UP000000577};
RN [1] {ECO:0000313|EMBL:AFP20468.1, ECO:0000313|Proteomes:UP000000577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51573 / DSM 12127 / PCA
RC {ECO:0000313|Proteomes:UP000000577};
RX PubMed=14671304; DOI=10.1126/science.1088727;
RA Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA Fraser C.M.;
RT "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT environments.";
RL Science 302:1967-1969(2003).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B
CC family. {ECO:0000256|ARBA:ARBA00009425}.
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DR EMBL; AE017180; AFP20468.1; -; Genomic_DNA.
DR RefSeq; WP_010942979.1; NC_002939.5.
DR RefSeq; YP_006589535.1; NC_002939.5.
DR AlphaFoldDB; I7FIH1; -.
DR STRING; 243231.GSU2343; -.
DR EnsemblBacteria; AFP20468; AFP20468; GSU2343.
DR KEGG; gsu:GSU2343; -.
DR eggNOG; COG2111; Bacteria.
DR HOGENOM; CLU_101659_1_1_7; -.
DR InParanoid; I7FIH1; -.
DR OrthoDB; 9798859at2; -.
DR Proteomes; UP000000577; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007182; MnhB.
DR PANTHER; PTHR33932; NA(+)/H(+) ANTIPORTER SUBUNIT B; 1.
DR PANTHER; PTHR33932:SF4; NA(+)_H(+) ANTIPORTER SUBUNIT B1; 1.
DR Pfam; PF04039; MnhB; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000577};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..126
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 135 AA; 14141 MW; 6AE723A680D5E366 CRC64;
MQSLFLATAV RLLLPLLLLF SLFLLLRGHN EPGGGFVGGL VAAAAFVLHS LSHGVAGARR
VLRVEPRHLV AVGLLTALVS GLLPLAMGLP FLSGIWSILP VPVIGHGGTP ILFDIGVYLV
VAGMALMIVF SLMEE
//
