ID   I7GCE2_MACFA            Unreviewed;       427 AA.
AC   I7GCE2;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Macaca fascicularis brain cDNA clone: QflA-19093, similar to human kelch-like 2, Mayven (Drosophila) (KLHL2), mRNA, RefSeq: NM_007246.2 {ECO:0000313|EMBL:BAE89714.1};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|EMBL:BAE89714.1};
RN   [1] {ECO:0000313|EMBL:BAE89714.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=17194215; DOI=10.1371/journal.pbio.0050013;
RA   Wang H.-Y., Chien H.-C., Osada N., Hashimoto K., Sugano S., Gojobori T.,
RA   Chou C.-K., Tsai S.-F., Wu C.-I., Shen C.-K.J.;
RT   "Rate of evolution in brain-expressed genes in humans and other primates.";
RL   PLoS Biol. 5:e13-e13(2007).
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DR   EMBL; AB172652; BAE89714.1; -; mRNA.
DR   AlphaFoldDB; I7GCE2; -.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR   PANTHER; PTHR45632; LD33804P; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF01344; Kelch_1; 6.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF117281; Kelch motif; 1.
PE   2: Evidence at transcript level;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1..94
FT                   /note="BACK"
FT                   /evidence="ECO:0000259|SMART:SM00875"
SQ   SEQUENCE   427 AA;  47354 MW;  38A8B175D061B7C7 CRC64;
     MHACTDLLNK ANTYAEQHFT DVVLSEEFLN LGIEQVCSLI SSDKLTISSE EKVFEAVIAW
     VNHDKDVRQE FMARLMEHVR LPLLPREYLA QRVEEEALVK NSSACKDYPI EAMKYHLLPT
     EQRILMKSVR TRLRTPMNLP KLMVVVGGQA PKAIRSVECY DFKEERWHQV AELPSRRCRA
     GMVYMAGLVF AVDGFNGSLR VRTVDSYDPV KDQWTSVANM RDRRSTLGAA VLNGLLYAVG
     GFDGSTGLSS VEAYNIKSNE WFHVAPMNTR RSSVGVGVVG GLLYAVGGYD GASRQCLSTV
     ECYNATTNEW SYIAEMSTRR SGAGVGVLNN LLYAVGGHDG PLVRKRVEEY DPTTNAWRQV
     ADMNMCRRNA GVCAVNGLLY VVGGDDGSCN LASVEYYNPT TDKWTDVSSC MSTGRSYAGV
     TVIDKPL
//