ID I7GKM2_MACFA Unreviewed; 343 AA.
AC I7GKM2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Macaca fascicularis brain cDNA clone: QmoA-10845, similar to human fibronectin type 3 and SPRY (spla, ryanodine) domaincontaining (with coiled-coil motif) 1 (FSD1), mRNA, RefSeq: NM_024333.1 {ECO:0000313|EMBL:BAE87490.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|EMBL:BAE87490.1};
RN [1] {ECO:0000313|EMBL:BAE87490.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17194215; DOI=10.1371/journal.pbio.0050013;
RA Wang H.-Y., Chien H.-C., Osada N., Hashimoto K., Sugano S., Gojobori T.,
RA Chou C.-K., Tsai S.-F., Wu C.-I., Shen C.-K.J.;
RT "Rate of evolution in brain-expressed genes in humans and other primates.";
RL PLoS Biol. 5:e13-e13(2007).
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DR EMBL; AB170427; BAE87490.1; -; mRNA.
DR AlphaFoldDB; I7GKM2; -.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR017903; COS_domain.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR PANTHER; PTHR24099:SF4; FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00041; fn3; 1.
DR SMART; SM00060; FN3; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS51262; COS; 1.
DR PROSITE; PS50853; FN3; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054}.
FT DOMAIN 1..37
FT /note="COS"
FT /evidence="ECO:0000259|PROSITE:PS51262"
FT DOMAIN 39..143
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 177..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 343 AA; 38351 MW; 22C64EEB3BEA35ED CRC64;
MAPAFRLSLK AKVSDNMSHL MVDFAQERQM LQALKFLPVP SAPVIDLAES LVADNCVTLV
WRMPDEDSKI DHYVLEYRRT NFEGPPRLKE DQPWMVIEGI RQTEYTLTGL KFDMKYMNFR
VKACNKAVAG EFSEPVTLET PAFMFRLDAS TSHQNLRVDD LSVEWDAMGG KVRDIKAREK
DGKGRTASPI NSPARGTPSP KRMPSGRGGR DRFTAESYTV LGDTLIDGGE HYWEVRYEPD
SKAFGVGVAY RSLGRFEQLG KTAASWCLHV NNWRAGQHSR PSMPTRSRCW TPPCPTAWVC
TVTSTKASCP FTTPAPNKCC TLSRPGSHSP CCLLSRYGVA ASR
//
