ID   I7GNT6_MACFA            Unreviewed;       277 AA.
AC   I7GNT6;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Macaca fascicularis brain cDNA clone: QflA-22318, similar to human mitochondrial carrier homolog 1 (C. elegans) (MTCH1),nuclear gene encoding mitochondrial protein, mRNA, RefSeq: NM_014341.1 {ECO:0000313|EMBL:BAE90442.1};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|EMBL:BAE90442.1};
RN   [1] {ECO:0000313|EMBL:BAE90442.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=17194215; DOI=10.1371/journal.pbio.0050013;
RA   Wang H.-Y., Chien H.-C., Osada N., Hashimoto K., Sugano S., Gojobori T.,
RA   Chou C.-K., Tsai S.-F., Wu C.-I., Shen C.-K.J.;
RT   "Rate of evolution in brain-expressed genes in humans and other primates.";
RL   PLoS Biol. 5:e13-e13(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC       outer membrane {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane
CC       protein {ECO:0000256|ARBA:ARBA00004374}.
CC   -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC       {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR   EMBL; AB173380; BAE90442.1; -; mRNA.
DR   RefSeq; XP_005553196.1; XM_005553139.2.
DR   AlphaFoldDB; I7GNT6; -.
DR   OrthoDB; 3571419at2759; -.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR   InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR   InterPro; IPR023395; Mt_carrier_dom_sf.
DR   PANTHER; PTHR10780; MITOCHONDRIAL CARRIER HOMOLOG; 1.
DR   PANTHER; PTHR10780:SF3; MITOCHONDRIAL CARRIER HOMOLOG 1; 1.
DR   Pfam; PF00153; Mito_carr; 1.
DR   SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR   PROSITE; PS50920; SOLCAR; 1.
PE   2: Evidence at transcript level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|RuleBase:RU000488}.
FT   REPEAT          80..168
FT                   /note="Solcar"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ   SEQUENCE   277 AA;  30652 MW;  817605748C0F7F44 CRC64;
     MPPTLGTNVL GRKVLYLPSF FTYAKYIVQV DGKIGLFRGL SPRLMSNALS TVTRGSMKKV
     FPPDEIEQVS NKDDMKTSLK KVVKETSYEM MMQCVSRMLA HPLHVISMRC MVQFVGREAK
     YSGVLSSIGK IFKEEGLLGF FVGLIPHLLG DVVFLWGCNL LAHFINAYLV DDSVSDTPGG
     LGNDQNPGSQ FSQALAIRSY TKFVMGIAVS MLTYPFLLVG DLMAVNNCGL QAGLPPYSPV
     FKSWIHCWKY LSVQGQLFRG SSLLFRRVSS GSCFALE
//