GenomeNet

Database: UniProt
Entry: I7HBR2_9HELI
LinkDB: I7HBR2_9HELI
Original site: I7HBR2_9HELI 
ID   I7HBR2_9HELI            Unreviewed;       443 AA.
AC   I7HBR2;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-SEP-2017, entry version 42.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:BAM31262.1};
GN   ORFNames=HCBAA847_0001 {ECO:0000313|EMBL:BAM31262.1};
OS   Helicobacter cinaedi CCUG 18818 = ATCC BAA-847.
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=537971 {ECO:0000313|EMBL:BAM31262.1, ECO:0000313|Proteomes:UP000006036};
RN   [1] {ECO:0000313|EMBL:BAM31262.1, ECO:0000313|Proteomes:UP000006036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-847 {ECO:0000313|EMBL:BAM31262.1,
RC   ECO:0000313|Proteomes:UP000006036};
RX   PubMed=23012276; DOI=10.1128/JB.01347-12;
RA   Miyoshi-Akiyama T., Takeshita N., Ohmagari N., Kirikae T.;
RT   "Complete Genome Sequence of Helicobacter cinaedi Type Strain ATCC
RT   BAA-847.";
RL   J. Bacteriol. 194:5692-5692(2012).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_00377}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AP012492; BAM31262.1; -; Genomic_DNA.
DR   RefSeq; WP_015453173.1; NC_020555.1.
DR   STRING; 537971.HCCG_00771; -.
DR   EnsemblBacteria; BAM31262; BAM31262; HCBAA847_0001.
DR   KEGG; hcb:HCBAA847_0001; -.
DR   PATRIC; fig|1206745.3.peg.1; -.
DR   KO; K02313; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000006036; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006036};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006036}.
FT   DOMAIN      137    263       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      346    415       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   443 AA;  50726 MW;  1689064417627CCB CRC64;
     MHLDNILKKL KNKLSDLEYS SYISLMEYDE SASRTDLEVF YVPNIFVANW IKSNYLESIA
     DAFMEENPNG IRPEIHIRVK EKNQNVKSLN FNKIPTHFQQ NLLSLNPFYT FENFVVGKSN
     EHAHTIAKVV ARQQALAYNP VLFYGKSGLR KTHLLHAIGN VVKEQNKNVL YTTAEELLND
     FISKIRRGTM DSFREKYRKC DYLLIDDVQF LGNREGVQEE LLNTFNALYS TQKQIVMTSD
     KPPKEIKGLE DRLRSRFEGG VMAEITNPEL ETKISIIELK CQINRINFDK EVIDYIASNI
     YGNIRQIEGI LSTINTHMSL SPEANALKVA KNVLKNYQNE RLEGVTLDNI IKLVGKELNI
     KPSEILSKER SRKVAFARRV VIYLARALTI NSMPMIAKEL NMKDHSSVSK ALKAIESEIA
     TDSATKGIIE ELKSKIQQTM DNV
//
DBGET integrated database retrieval system