ID I7HCB7_9HELI Unreviewed; 581 AA.
AC I7HCB7;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Arylsulfatase {ECO:0000313|EMBL:EFR47144.1};
DE EC=3.1.6.- {ECO:0000313|EMBL:EFR47144.1};
DE SubName: Full=Putative sulfatase family protein {ECO:0000313|EMBL:BAM31737.1};
GN ORFNames=HCBAA847_0490 {ECO:0000313|EMBL:BAM31737.1}, HCCG_01692
GN {ECO:0000313|EMBL:EFR47144.1};
OS Helicobacter cinaedi CCUG 18818 = ATCC BAA-847.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=537971 {ECO:0000313|EMBL:BAM31737.1, ECO:0000313|Proteomes:UP000006036};
RN [1] {ECO:0000313|EMBL:EFR47144.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCUG 18818 {ECO:0000313|EMBL:EFR47144.1};
RG The Broad Institute Genome Sequencing Platform;
RA Fox J.G., Shen Z., Charoenlap N., Schauer D.B., Ward D., Mehta T.,
RA Young S., Jaffe D., Gnerre S., Berlin A., Heiman D., Hepburn T., Shea T.,
RA Sykes S., Alvarado L., Kodira C., Borodovsky M., Lander E., Galagan J.,
RA Nusbaum C., Birren B.;
RT "Annotation of Helicobacter cinaedi strain CCUG 18818.";
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BAM31737.1, ECO:0000313|Proteomes:UP000006036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-847 {ECO:0000313|EMBL:BAM31737.1,
RC ECO:0000313|Proteomes:UP000006036};
RX PubMed=23012276; DOI=10.1128/JB.01347-12;
RA Miyoshi-Akiyama T., Takeshita N., Ohmagari N., Kirikae T.;
RT "Complete Genome Sequence of Helicobacter cinaedi Type Strain ATCC
RT BAA-847.";
RL J. Bacteriol. 194:5692-5692(2012).
RN [3] {ECO:0000313|EMBL:BAM31737.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC BAA-847 {ECO:0000313|EMBL:BAM31737.1};
RA Akiyama T., Takeshita N., Ohmagari N., Kirikae T.;
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Proteomes:UP000005755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 18818 {ECO:0000313|Proteomes:UP000005755};
RX PubMed=25212613;
RA Shen Z., Sheh A., Young S.K., Abouelliel A., Ward D.V., Earl A.M.,
RA Fox J.G.;
RT "Draft genome sequences of six enterohepatic helicobacter species isolated
RT from humans and one from rhesus macaques.";
RL Genome Announc. 2:e00857-e00814(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP012492; BAM31737.1; -; Genomic_DNA.
DR EMBL; DS990393; EFR47144.1; -; Genomic_DNA.
DR AlphaFoldDB; I7HCB7; -.
DR KEGG; hcb:HCBAA847_0490; -.
DR PATRIC; fig|1206745.3.peg.517; -.
DR eggNOG; COG1368; Bacteria.
DR HOGENOM; CLU_014653_0_1_7; -.
DR OrthoDB; 9760224at2; -.
DR Proteomes; UP000005755; Unassembled WGS sequence.
DR Proteomes; UP000006036; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000313|EMBL:EFR47144.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 186..476
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 581 AA; 65936 MW; 58CF162EBCDAA219 CRC64;
MLGFVFMVAA IVNFYYFRTY GSKIDIFIFG LKDDDTLAVL SIMWQDYPVV LGILASLLCG
IITLFVYKIP LKIHFLKQKL QVSLHTIAFF IYMLIHICFV ILVFIAARGS LGTYPISENN
HNISSLPLLN HIATNPLIAF DWARTNYKLN THFAEPNIQK GEMLQEKLFP LLHTTADSSF
LQSNPPHIIV NLMESFGTNM LVYDNKDTND LLGSLRKHFE SDFVFYRFLS GANGTAGSFV
GLFFNSPDAQ ISLGNAKNIK LPYNPFAIYA DSGYEVIYIT SGYASWRGLG DYIKIQGAHK
VYDAITLMDK YPTSKQDVSA YGVPDEYAYK LAFEILNNAT KPIFIAILTT SNHPPYHLPH
NYTLKPISLP DELLLRPSKE SQARLELATK LFQYANNAFG KFMDNIKQSH LAKNTIVSAT
GDHRIRDFGS NPSTDKALYH SVPLYLYVPQ AYKINLTYEP SRTGSHKDIV PTLYELSLSN
TTYMSLGGRN ILAKIDNEKY AFGYNQAVWI DKKGIYPIPT DIGYLWQDSQ VSKDSKKYFG
LLSLDESFEL GDKKDFATLY NELFNYSISW QIHNAKESEK Q
//
