ID I7HJH6_PIG Unreviewed; 137 AA.
AC I7HJH6; F1RI25;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Spermadhesin AQN-3 {ECO:0000313|EMBL:CAI05914.1};
GN Name=AQN-3 {ECO:0000313|EMBL:CAI05914.1};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|EMBL:CAI05914.1};
RN [1] {ECO:0000313|EMBL:CAI05914.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15922517; DOI=10.1016/j.gene.2005.04.015;
RA Haase B., Schlotterer C., Ekhlasi-Hundrieser M., Kuiper H., Distl O.,
RA Topfer-Petersen E., Leeb T.;
RT "Evolution of the spermadhesin gene family.";
RL Gene 352:20-29(2005).
RN [2] {ECO:0000313|EMBL:CAI05914.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16624504; DOI=10.1016/j.gene.2006.03.002;
RA Haase B., Humphray S.J., Lyer S., Renner M., Poustka A., Mollenhauer J.,
RA Leeb T.;
RT "Molecular characterization of the porcine deleted in malignant brain
RT tumors 1 gene (DMBT1).";
RL Gene 376:184-191(2006).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the spermadhesin family.
CC {ECO:0000256|ARBA:ARBA00010668}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR EMBL; AJ853851; CAI05904.1; -; mRNA.
DR EMBL; AJ853849; CAI05914.1; -; Genomic_DNA.
DR RefSeq; NP_001026946.1; NM_001031776.1.
DR SMR; I7HJH6; -.
DR GeneID; 396758; -.
DR KEGG; ssc:396758; -.
DR CTD; 396758; -.
DR HOGENOM; CLU_154697_0_0_1; -.
DR OrthoDB; 5491454at2759; -.
DR TreeFam; TF351664; -.
DR Bgee; ENSSSCG00000002977; Expressed in forelimb bud and 3 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0007338; P:single fertilization; IEA:InterPro.
DR CDD; cd00041; CUB; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR000124; Spermadhesin.
DR PANTHER; PTHR46908:SF4; CUBILIN HOMOLOG; 1.
DR PANTHER; PTHR46908; CUBILIN-LIKE PROTEIN; 1.
DR Pfam; PF00431; CUB; 1.
DR SMART; SM00042; CUB; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS00985; SPERMADHESIN_1; 1.
DR PROSITE; PS00986; SPERMADHESIN_2; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..137
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014579721"
FT DOMAIN 30..131
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
SQ SEQUENCE 137 AA; 15034 MW; 85ADF05F429BB885 CRC64;
MKLGSAIPWA LLLSTATLVS TAQNKGSDDC GGFLKNYSGW ISYYKALTTN CVWTIEMKPG
HKIILQILPL NLTCGKEYLE VRDQRAGPDN FLKVCGGTTF VYQSSSNVAT VKYSRDSHHP
ASSFNVYFYG IPQGAKA
//
