ID I7JUS7_9LACO Unreviewed; 2480 AA.
AC I7JUS7;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=Gram-positive cocci surface proteins LPxTG domain-containing protein {ECO:0000259|PROSITE:PS50847};
GN ORFNames=BN55_09680 {ECO:0000313|EMBL:CCI81666.1};
OS Lactobacillus hominis DSM 23910 = CRBIP 24.179.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1423758 {ECO:0000313|EMBL:CCI81666.1, ECO:0000313|Proteomes:UP000009320};
RN [1] {ECO:0000313|EMBL:CCI81666.1, ECO:0000313|Proteomes:UP000009320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRBIP 24.179T {ECO:0000313|Proteomes:UP000009320};
RA Cousin S., Ma L., Bizet C., Loux V., Bouchier C., Clermont D., Creno S.;
RT "Draft Genome Sequence of Lactobacillus hominis Strain CRBIP 24.179T,
RT isolated from human intestine.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI81666.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAKE01000005; CCI81666.1; -; Genomic_DNA.
DR STRING; 1423758.FC41_GL001751; -.
DR PATRIC; fig|1423758.3.peg.1785; -.
DR eggNOG; COG3064; Bacteria.
DR Proteomes; UP000009320; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.4300; -; 3.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR046776; Pectate_lyase_5.
DR InterPro; IPR012706; Rib_alpha_Esp_rpt.
DR InterPro; IPR044055; RibLong.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR NCBIfam; TIGR02331; rib_alpha; 1.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR Pfam; PF20585; Pectate_lyase_5; 1.
DR Pfam; PF08428; Rib; 5.
DR Pfam; PF18957; RibLong; 1.
DR Pfam; PF04650; YSIRK_signal; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2455..2472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2445..2480
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 956..1001
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2372..2434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2376..2434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2480 AA; 264856 MW; FA90459832DAA077 CRC64;
MLSKNNYQEK LRKMQPRKNR YSIRKFTVGA ASVLIGFFLA GFSQNQTVKA DTNSHTDNEM
TPHKAQAVNS KDLTTGVEGK NVNVQEVNNE KLAQAANDNK VAKTEKEHIL DTLPTQESKS
TVNRSKENKD VLTKQVGANL VANKKDNPAK VALAKLAAES KEAQQQNLRG TQTAEASDWQ
SLVNALNNAN NGTINLTGDI TVANKGANVN GINRPNPVVN SGKMNLTGEN ISGGLVINGQ
GHAINFGANY LSFTTNNQKD SNPWDITFKN MTINADGYDN SWSTLGGAFS PIYMGGDDIR
TDLLANNKVT FENVTADIKN GAFYNTTMAQ QTTDNPYTTV TFKGNNNITC EAVNVKGNQL
YNYSSAVSAS HIIFVDGSDT TFNVSSAKTN NDQNAGGNIL RAKVEDEAND TAPAIDVQQG
ATVTLNGNST DVKGMLVNRA ITGTVQVDGN LNAKMADGHS MAIWAGNLNI GKNGVVNINT
KQSNDGSGIN GVGNYNGYHF APISLGVGFA ANVSNANSNV LDNQGKLTIV RTGVNNQSTS
PLISFGSGNG TGAEFSLNVA DGATMDLQDG ATSSIKGDFT NTPNIGIVTM WGNGSTSGSA
ASTYANININ NPAYVNFQRT GSQTGTLLRL ENMNNHVNIS SNGGALPLAL WDEANKSAGP
SYYWYINQLK NQNNWGDNSI SGFAQTGNSI GQNKKGEIKF LHSNGDITFA GSQAGLNTFQ
YQDGVVTQGQ PAKGVKYETP YLNRFLNVFN WWTPQRVAMG TNLASVAKPT DAQKYQPQTQ
VITGYTDQTL NDLTAANGIS GYINENGQPA TLTGTTVAWY NPATDAAAWT EAMGDQPTPT
NPTGKLKVTD GSAWAKVTYQ DGTVDFANIP LDIKSQAEEY NPLGQNVNTI VGSEPSAKDG
ISNTSDLPTS AQYSWSTTPD VSKAGIVPSI VNVTYDDGSM DEVPVNVIVK DSKGNIPDKA
GDAAENDPQG KEVSTVIGKL PDPNTAVDWP KNPVDADGKP IDPTQIKYDW STTPDIWTQG
NHPGVVKVTY PDGTNDLVPT TVIVTNSPTG KSTTIEQGGD VPDPSTVIDW TNNGQAPNGT
KPNDPKVTYT WVDKPTTTNP GQQTGTVKIT YPNGESTVVR VPVTVTATNS SYDPFAKHLV
LPYSPTGDGV PEAGSVIELP NGETAPAGVQ YTWGTKPDTT KPGMQTANII ATWTTDGKTN
TKNIPVTVTV GSMAGYYNPK ANDLTVPYNA DMNKYPAKNQ ITGLPSGLKT DDVWAPMPVT
SVAGTQPTMI KVTYSDGSFD YVPLNVTVEN TAYTPSYNPV SVKPGQQVTD NIVIPDGQKT
PSGTKFTAGE TTPNWATVDP TTGTITLKPS ADVTPGHYFV PVIIAVPGKG NQTITAPVTV
IGMDPEHNTY YGSQSMTSFD IPTISVHRTT DSNPINADLA KIQTITYYQD WDGKGNATSN
YKTFTTYQLE GNKYVNIKDP SDSFAANVFN YSWMPAGNGV LTPNTNWKVT ADNTDTIKYD
MGQAPNSLEQ TTDGESLPGN SKWRVEYSFN DPDLFGYIGL SSQSSWMNTY FDFYGATTGQ
ALTFNQNQDI SNLTQDQYRQ LIDVTDLGQA GWNGQNINPN APQVLAYVPG TDAAKTFSMT
WAPNGQPSTK DIANGVSGTV RIHFNDGTYL DVKANINVVA DSDSGKGDHN KTEFTQKIVY
TYNGHEVAYT TIDNIAKGSS LTAAQLKSAI DGNVPANYNI ATGYTYPGAV NDITATPAVI
NVPLALKNGS QFNAQGQIVY QTADGTQVGT GATIKSNIGD TLTAGLLHDL ADQSVPEGYT
ISQYPGSFEV STKSFTIPVI VTKATPDTQN FAQNIVYKDA EGKVISTFNK AITGTFTSKT
PATVSADEIK NTINNGVPKN WKIATSYKYP AAETISTKTP ADIIVLVEHA TKYITPTDPG
VDPTDPKYKN MFETVTRKIY QTKPGENQTL FDTQSVDFGR KGVEDLVTRD VTGTGDWQVG
KISDHKFTLG GSAEFAEENA PQIDGYDSYV DGTKSTQVSS APALKDGQPV NGQPAYITYL
KAGKTTPVPY DPSNREMNKY VTRTINVYKP GLSKAETITQ TVHFVRGGVG QNAGMKDTEG
NIAWTAWTVA DGDNVSTGAE TGTWKEYDVD QINNYTSTVD GKDATKVDAK AVNADTSNVT
VTVAYTQTLQ PTDPTINPNK PGENSDMYAH PTRTINVKNP VTGNTDTSTQ VVWFGRTKTV
STDPNVKPTY GKWQLGKVEN NKFVIDSTAK AEWPEFAAPT FDGYTPSQDK VTAVNDIKPD
TANVIVTITY SKNNNGGGNV TPTPQGQVTI IYRDSNGTEV GRTTISGAEG STVDPSSTIE
GNIPSGYKLK DGYQVPTNAS ISSTIEVPVV VADNGGNNGN DDNGNKGPTV PTDSNNHNNG
HDNEFNNGNK ANSAADNGGI TENDNTYSAH TTGNNIQHGI SAKKLPQTGN KTNKWGIFGL
AVASLAGLFG LGSDKKRRSR
//
