ID I7KDM1_METBM Unreviewed; 386 AA.
AC I7KDM1;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=ORC1-type DNA replication protein {ECO:0000256|HAMAP-Rule:MF_01407};
GN Name=cdc6d {ECO:0000313|EMBL:CCJ37006.1};
GN OrderedLocusNames=BN140_2083 {ECO:0000313|EMBL:CCJ37006.1};
OS Methanoculleus bourgensis (strain ATCC 43281 / DSM 3045 / OCM 15 / MS2)
OS (Methanogenium bourgense).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX NCBI_TaxID=1201294 {ECO:0000313|EMBL:CCJ37006.1, ECO:0000313|Proteomes:UP000009007};
RN [1] {ECO:0000313|Proteomes:UP000009007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43281 / DSM 3045 / OCM 15 / MS2
RC {ECO:0000313|Proteomes:UP000009007};
RX PubMed=22965103; DOI=10.1128/JB.01292-12;
RA Maus I., Wibberg D., Stantscheff R., Eikmeyer F.G., Seffner A., Boelter J.,
RA Szczepanowski R., Blom J., Jaenicke S., Konig H., Puhler A., Schluter A.;
RT "Complete genome sequence of the hydrogenotrophic, methanogenic archaeon
RT Methanoculleus bourgensis strain MS2T, isolated from a sewage sludge
RT digester.";
RL J. Bacteriol. 194:5487-5488(2012).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000256|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000256|HAMAP-
CC Rule:MF_01407}.
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DR EMBL; HE964772; CCJ37006.1; -; Genomic_DNA.
DR RefSeq; WP_014867979.1; NC_018227.2.
DR AlphaFoldDB; I7KDM1; -.
DR STRING; 1201294.BN140_2083; -.
DR GeneID; 13353901; -.
DR KEGG; mbg:BN140_2083; -.
DR PATRIC; fig|1201294.9.peg.2294; -.
DR HOGENOM; CLU_025112_3_0_2; -.
DR BioCyc; MBOU1201294:BN140_RS10365-MONOMER; -.
DR Proteomes; UP000009007; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR10763:SF32; ORC1-TYPE DNA REPLICATION PROTEIN 2; 1.
DR Pfam; PF13401; AAA_22; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_01407}; Cell cycle {ECO:0000313|EMBL:CCJ37006.1};
KW Cell division {ECO:0000313|EMBL:CCJ37006.1};
KW DNA replication {ECO:0000256|HAMAP-Rule:MF_01407};
KW Hydrolase {ECO:0000313|EMBL:CCJ37006.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_01407}; Reference proteome {ECO:0000313|Proteomes:UP000009007}.
FT DOMAIN 55..163
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|Pfam:PF13401"
FT BINDING 63..67
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 206
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
FT BINDING 218
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01407"
SQ SEQUENCE 386 AA; 42629 MW; 94B9285AF8468DE6 CRC64;
MRYSSLLRSD QTLFRDPEVF ESTYTPEHLH HRDAQVRELA FLIRPALRGA SPMNAILRGP
PGTGKTTTVR RVFAEVAAET RRVVPVYVNC RQDHTLLAVY RCISRHLSGY APPSRHLDDV
REVIAARLRE RDARLLVCLD DADYLIAAGT YNVLLYQLLR LYEGWSDLRG AGVFAVTSDL
ALNLYAEADG PVRSVFHPTE VNFWPYTKTE IRGILSDRVR QGLYPGVVPA TVLDLVVEMT
AGEQDVRVGI ALLRQACLQA EGDSRRRVTR KDVMDVVAGV GSPALAARTT GLSSGERALL
YRIAEQSLSG AEMMAGAVFE EVQDYLAVGK TTYHARLRRL ADAGIIDLLH TGKGYEVFLR
YAPDEVFAAC ARGGPGDQSP GCPRKG
//
