ID I7KHI0_9LACO Unreviewed; 857 AA.
AC I7KHI0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=DNA translocase FtsK {ECO:0000256|ARBA:ARBA00020887};
GN ORFNames=BN55_02245 {ECO:0000313|EMBL:CCI82145.1};
OS Lactobacillus hominis DSM 23910 = CRBIP 24.179.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1423758 {ECO:0000313|EMBL:CCI82145.1, ECO:0000313|Proteomes:UP000009320};
RN [1] {ECO:0000313|EMBL:CCI82145.1, ECO:0000313|Proteomes:UP000009320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRBIP 24.179T {ECO:0000313|Proteomes:UP000009320};
RA Cousin S., Ma L., Bizet C., Loux V., Bouchier C., Clermont D., Creno S.;
RT "Draft Genome Sequence of Lactobacillus hominis Strain CRBIP 24.179T,
RT isolated from human intestine.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI82145.1}.
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DR EMBL; CAKE01000015; CCI82145.1; -; Genomic_DNA.
DR RefSeq; WP_008471139.1; NZ_CAKE01000015.1.
DR AlphaFoldDB; I7KHI0; -.
DR STRING; 1423758.FC41_GL001847; -.
DR GeneID; 82847369; -.
DR eggNOG; COG1221; Bacteria.
DR eggNOG; COG3933; Bacteria.
DR OrthoDB; 9771372at2; -.
DR Proteomes; UP000009320; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.510; Phosphotransferase system, mannose-type IIA component; 1.
DR Gene3D; 1.10.1790.10; PRD domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR004701; PTS_EIIA_man-typ.
DR InterPro; IPR036662; PTS_EIIA_man-typ_sf.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR32071:SF38; PSP OPERON TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF03610; EIIA-man; 1.
DR Pfam; PF01022; HTH_5; 1.
DR Pfam; PF00874; PRD; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53062; PTS system fructose IIA component-like; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51372; PRD_2; 1.
DR PROSITE; PS51096; PTS_EIIA_TYPE_4; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 76..310
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT DOMAIN 501..630
FT /note="PTS EIIA type-4"
FT /evidence="ECO:0000259|PROSITE:PS51096"
FT DOMAIN 755..857
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
SQ SEQUENCE 857 AA; 97391 MW; 8608679369CB8E16 CRC64;
MDKARDQVLA YINQLKNDQP LTTSQLASDL NLSRSVISHY LNDLASDGEV QKIAGRPVRW
QRNSTTILNR NTFKNFIGYR GSMRHVISQI SAAVLYPPDG LNILITGHSG VGKSYLASKI
AKLAKDKKVI KADAPYIVLN CADYANNPEL VSSMLFGYVK GAYTGADESK DGLLKQANGG
YLFLDEVHRL SSENQEKLFS FIDSGEFYAM GDNVKPIKSK VRLILATTED PEKVLLTTFL
RRIPVHVNLP DFIKRPIDER LELLRYLFYQ EAQTINKKIE VDKYVVSALL QIKHTGNIGY
LKNVIQVSCA AAYNEQAMSD VIRLEMSNLM LTDLPRFEDY SSIFVDPQKP LERHQSSLIQ
RSLKDIENQL EGLQENYSHD AAIKCKLAIQ GLKQFVPEWV LKSGLHLQHQ GLFNKVVQKQ
FGLGQTGYLE PVLYLLYSYH FEIDEKIIQL LNEKFSNLIP RALHVARTFY KKLPQLTEKS
DQSLILILAL LLSDHVDENI QLRGLMVAHG HSTATSIQTV VNSLCGTYIF DAIDMPVDTG
VEPIIEETKK LISSFNTTNG FILMVDMGSL SQLYSEISSH LDGDLLVVNN LTTLTALDLA
LKMQQNQPFK QIAQNAESEY GIEVQYYEGF SQSPNILISC ISGLGIAETV SKIIQPFLPS
QIKVIPGDYA SLKEKIKSQD WSYFDRTLFV LTTLDILEPV GFKHMNLYSL LDTSGENNLK
KWLAPYMTSQ EIETFSQQIL RFFSKEGISE RLSFLNPDVV IRQVEEINSK YESYYGLNLD
GKVKLNLYMH IALMIERLMV QKTAEIKVEP KTEQEKDFFN ISHSIFQPVE MKYNIKISNY
EISLLYELFR QFIEAKL
//
