ID I7LV17_TETTS Unreviewed; 472 AA.
AC I7LV17;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Carboxypeptidase {ECO:0000256|RuleBase:RU361156};
DE EC=3.4.16.- {ECO:0000256|RuleBase:RU361156};
GN ORFNames=TTHERM_00191440 {ECO:0000313|EMBL:EAR96476.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR96476.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SIMILARITY: Belongs to the peptidase S10 family.
CC {ECO:0000256|ARBA:ARBA00009431, ECO:0000256|RuleBase:RU361156}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG662693; EAR96476.1; -; Genomic_DNA.
DR RefSeq; XP_001016721.1; XM_001016721.2.
DR AlphaFoldDB; I7LV17; -.
DR STRING; 312017.I7LV17; -.
DR ESTHER; tetts-q23ih4; Carboxypeptidase_S10.
DR MEROPS; S10.003; -.
DR EnsemblProtists; EAR96476; EAR96476; TTHERM_00191440.
DR GeneID; 7832093; -.
DR KEGG; tet:TTHERM_00191440; -.
DR eggNOG; KOG1282; Eukaryota.
DR HOGENOM; CLU_008523_10_1_1; -.
DR InParanoid; I7LV17; -.
DR OMA; AWKSWTD; -.
DR OrthoDB; 1203831at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0004185; F:serine-type carboxypeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001563; Peptidase_S10.
DR InterPro; IPR018202; Ser_caboxypep_ser_AS.
DR PANTHER; PTHR11802:SF472; SERINE CARBOXYPEPTIDASE CPVL-RELATED; 1.
DR PANTHER; PTHR11802; SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE; 1.
DR Pfam; PF00450; Peptidase_S10; 1.
DR PRINTS; PR00724; CRBOXYPTASEC.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00131; CARBOXYPEPT_SER_SER; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000256|RuleBase:RU361156,
KW ECO:0000313|EMBL:EAR96476.1}; Hydrolase {ECO:0000256|RuleBase:RU361156};
KW Protease {ECO:0000256|RuleBase:RU361156};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Signal {ECO:0000256|RuleBase:RU361156}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|RuleBase:RU361156"
FT CHAIN 19..472
FT /note="Carboxypeptidase"
FT /evidence="ECO:0000256|RuleBase:RU361156"
FT /id="PRO_5006526289"
SQ SEQUENCE 472 AA; 52908 MW; 1AD1E8A28F8323E4 CRC64;
MKFQRLLIAA LIVCLVSAQL RLEDQIKKEQ QNESWLEKLL DYFRPKNKLS VTTECNALNF
TAYDGLSYSG YLSVGQNLKS ALGFIFYGAK GRTVEQIRTL PTIIWLNGGP GCSSQFGNFF
ELGPLYVNQT SSGSFYFTPN NYTWTNEYNV IFVDQPIGTG ISYADSSKEI PQNQDQVAQQ
FLYALDQLYN SPNGCFNQVG LTPKSPLFLF GESYAGKYVP SIAARALKEK NVFNIQGIGV
VDGFTVPYYV VGSLSEFSHL NNLTSNTQYQ HGLQVAAQAQ KAINASQFQL ASSYFNQDMS
INNPQNLDVY NIHRQDEPDA SALENLFNSA YGQQLFKLRN KKYTQCDNTV YARFANDFMK
GDTINAVEYL LEQDFPVNYF NGNLDLIVPY IGTETLLSVL NWSGQSQFNS APTTQWAADG
AVYGTVKTYK NLQYKLVYNS GHMVPQDQPA AALNLVTEAV NRSLQYNQSK SQ
//
