ID I7M2X3_TETTS Unreviewed; 304 AA.
AC I7M2X3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Ser/thr phosphatase family protein {ECO:0000313|EMBL:EAS01472.1};
GN ORFNames=TTHERM_00151850 {ECO:0000313|EMBL:EAS01472.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS01472.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662603; EAS01472.1; -; Genomic_DNA.
DR RefSeq; XP_001021718.1; XM_001021718.3.
DR AlphaFoldDB; I7M2X3; -.
DR EnsemblProtists; EAS01472; EAS01472; TTHERM_00151850.
DR GeneID; 7828808; -.
DR KEGG; tet:TTHERM_00151850; -.
DR eggNOG; ENOG502S3P6; Eukaryota.
DR HOGENOM; CLU_999021_0_0_1; -.
DR InParanoid; I7M2X3; -.
DR OMA; ACEGEMS; -.
DR OrthoDB; 178795at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR37523:SF1; METALLOPHOS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37523; METALLOPHOSPHOESTERASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 29..254
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
SQ SEQUENCE 304 AA; 34892 MW; FDB1EE7BD91C5B86 CRC64;
MIEKEIITDS GRIPLNPFAY GDKKEKDLVI LLLSDIHLDH KKIEKLKGWH KDYNNDIIDY
AFILGDFDNL FQDKNNIDLN ECCQSEARIT NLLNFLEFLS CPLLLIPGNH DPQTMFDAHK
KSSELPRMTQ HSFNIHKQAF QLNQTLSVVG FGGSIPGYQF PNGVKTKLWD GYPYDSEKEL
EDDANEFFKK QFENEPQKQF ILMTHVGPYN SSTTIVKTES VSDQHVYSGS EYLDKLLQSY
SQQVIVNVHG HTHDSHGRNN IYKVPVVNPG SLLDGNFCKI NLHKDSASQK WVLRSSHFIN
LNSF
//
