ID I7M6L8_TETTS Unreviewed; 3036 AA.
AC I7M6L8;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY {ECO:0000256|ARBA:ARBA00019143};
GN ORFNames=TTHERM_00441970 {ECO:0000313|EMBL:EAR85447.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR85447.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG662665; EAR85447.2; -; Genomic_DNA.
DR RefSeq; XP_001033110.2; XM_001033110.2.
DR GeneID; 7843308; -.
DR KEGG; tet:TTHERM_00441970; -.
DR eggNOG; KOG4626; Eukaryota.
DR InParanoid; I7M6L8; -.
DR OrthoDB; 177932at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0009740; P:gibberellic acid mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 7.
DR InterPro; IPR006597; Sel1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45586:SF1; SLR0626 PROTEIN; 1.
DR PANTHER; PTHR45586; TPR REPEAT-CONTAINING PROTEIN PA4667; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF00515; TPR_1; 2.
DR Pfam; PF13414; TPR_11; 1.
DR Pfam; PF14559; TPR_19; 1.
DR Pfam; PF13174; TPR_6; 1.
DR Pfam; PF13181; TPR_8; 5.
DR SMART; SM00671; SEL1; 10.
DR SMART; SM00028; TPR; 21.
DR SUPFAM; SSF48452; TPR-like; 5.
DR PROSITE; PS50005; TPR; 11.
DR PROSITE; PS50293; TPR_REGION; 3.
PE 4: Predicted;
KW Gibberellin signaling pathway {ECO:0000256|ARBA:ARBA00022941};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 199..232
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 2476..2509
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 2548..2581
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 2582..2615
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 2616..2649
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 2685..2718
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 2719..2752
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 2786..2819
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 2820..2853
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 2854..2887
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 2922..2955
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 584..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..1329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1342..1646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1738..1780
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1818..2251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2318..2347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2966..2989
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3016..3036
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 777..794
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..959
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 960..975
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..993
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1064
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1065..1081
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1082..1096
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1097..1116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1117..1155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1170..1205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1223..1259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1260..1292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1293..1312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1360..1378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1379..1403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1418..1498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1499..1515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1528..1555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1580..1598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1599..1614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1615..1634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1738..1753
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1818..1842
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1843..1858
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1877..1891
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1900..1930
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1931..1994
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2005..2028
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2029..2100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2132..2151
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2159..2214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2215..2251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2968..2989
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3036 AA; 354943 MW; AC11CE816BB4CACD CRC64;
MSDYDYEQDF SDLNDEKPQS QEIERHEDSQ FQQNQAVSPR EGQNSQNNGE LEKDSDFGAN
HSYVSFSHEE KEIVEKQIHQ NSKQSKLFTD TSEEFNKIRS NIIEKQFQQA LVQIEEYLRL
NPKSVEAINL KVNCLKQLKG AKDNNLNRKC IEELKKSLEL EPNNVLTLFN IATCYYELSD
YKNAIKYYEM LSKQNFQDAR VYFNLALSYE KINDTYNAQV NYDKTLKLNS SFSGAVVNYS
NLLIRIGELE QSRLLLESHL KYQPRDEKAI NNLNIILAEK RQDKQADILF KKILRKQNGF
TPSILYNHGV LLFKQNKLIS ALQAFQQFTQ IPEVEERDPL NLLSYVNQGL IFEKLGQYES
SLTVYETILE NFSDIVNCKE FEQKIAEMKD KILKRLSTKN YHFSYNNPPP QGQQYTFYSS
SQNHDTMPPL NSQQKRLFPV KQKGSQSNQF QLSSNNFRQI QTPQSLESNG TKILFNQKQN
EMAQTDGLKG FNKGSFQFQL KTQQINKLSP DSKKDDIKIN NFFKNNKFKN SDNLNNNNNN
HQGERIILEK PLTGQNKQNL SISFHENKFK KNILLRKGSS ELKTSLNSHS DKQNLSNNYG
GNMTQPNREG RQFNFNYLDK LSKPKKLPKE DPNVKSSLEL APKQINKNWS QQNQVNNPVF
DRLTKPKQPQ VELSQSPESN KTLLNAHKQN QTKESNSNFT IKPNQQIKLA SIDSSKQIQQ
KAENQISKKD NNSMAAESSQ TSIKQNNLMN LDNQQKSKPQ VKSEFAIKQS DSQSKIKQTK
SQERSEEKEK QISVTDKSQN AQNSAQNPKQ QQSNLDQQKQ VNGQTQKINN SDNQVNLEDK
TPLKIQENSK ITIQKNNNVA SQSVSKASEQ QFSQTSTPSK KQNQKNSETP QNQSTPKQKV
LSNQPEKVQT PQSQKQQKAY AEDQNQNKKV NNQQINKQNS IGSQKSLKET NNLSSTPIQH
QKIKEEKEED DISRQQSESG LNSPNQADQH GKQKEQNFTS ESLKQDQIQK DNQKGESKHS
TFKENNPQQE QERKQSLIQK QIEINETEKK PNIQKIEKEQ NQSLVKDEQN TNNQQNTNQN
KDDQVKEMKV EQQKDNQNDI SKNQLDQNSQ QIKEQLKNKN INDKNNHETN QNEHSQKENK
VEETKNKKEG VVSKDETQDN LSNNQSAISK KEVELDKKDK TDQQNTKQQV EEKHPERHES
NQQIESSVKE NRVQDQQQDN TKHQQKEQVM QNQDKNEQQK QDQQQKNSEQ IIQKKQSDQT
PNQKKIDKKS TFEEKEENSS QQLIKDHQES IKENNTSQPL IQLQQQYSSM DSRHHGEGQR
SRHQIGFQIN IIQENGSLIK SEEFKEEVQD DDPEQLNDSQ ILKDKQLIEV QQQKDVKSDN
QIPKGEQKES NHDKDKNQEK QHQNESKNIP TIHQDSQNQK NKDLKEMSEN NLNKKQEISK
STEDMKQSTE HPQQKESKDS AEFQQQVKSK KSVDNDQDKK HEEKQESKIL EDSNQEKDVQ
INHQQNNNQQ IKSKNVINED EAKKENNQTI NQQEQAPKQN NNNSQEQIPV QVENQNSHQE
HKKQEQETIQ NNLENQNKHH QFDNQNDHQQ EIEQNQKQKN DSPKNLNQSH EEQNFENSMK
QDQKQEDKTQ IPQTPKKEKM QLQQNDISDK DNINFFKDQN NNQQLDEEQQ RIFNEQLEKQ
QEYMIMVTQY KSVEKLNESL QDSARSSKLN NISQEIAHNN QNQDFIIGGQ TESIQEIEHH
QDKHIDSQKQ DQSDLNQEEL QQKQQQIHDD KGDNNNISEN PNEILENQQE KEIKIIEQNH
DSQQNEKDSQ QITQIDQINQ DNQQENSKQA SQIQIQDQKQ IKQDNINESD QAHEQEKEDE
NEQLEDEQSQ NEEIENNQQN RDNDSEKNLN DSTSKLQEVQ DKLNSEKEIQ DQQKIEQSIS
QDEKEQQQHE QIQDNNQSNE QIINQDEQEE QNQNEQTQFN QQESKDELNQ NQNLKQEQDD
QQAQDLQLNQ QDEQQQHDEL QEKDQNSPQN QQELDQQQNL QGQDQNEEQS NIENKEDLDK
ENQDQQDNDE QEKQQDEQEQ NSEIKNQEDQ QERSNEDQQE QLDKDENQQN QEESNKQQNL
EEEQQQDQNQ ENQIEKQLDD QQQDADQEEQ AQDVEKDQSE NKEESEAQPV INENDKNDTV
LNQQDEIKPN DHEQQQDLED TQKASQLNGD EENDQKEEKQ DNIEENKEQQ VLQINKDDNQ
ENLISNALEN QENQQNIQNI EGLEQQGRTQ SEEQDIVKML QGEKSPPSKS KSQEDNVLEN
DNHQNQYLVN KLIQNNSNDE ENEKRGLLTL HSSAKELESN RDSFMSDNNL TKKSKSKKSK
KNLQSQLPPE FDSWTKQICE NMIRNQDEKA YMAHYKLGII SIEDNDVENA KLNFLKVAEL
QPDFMPERIH FAIAEIFLQT QNWEQALEHY KIQYKYSQDK YTSCLRIGKC FKKLNNLEKA
KKSFENAIAQ NDQKDYKCFY KLGSIFFQEN KVKEAIDNFS KALSLNAQDI KILVKLGQIY
LEQDKEENSI QEAFQYLTDA IQLDENNYEC LISLGKLYDK QGELENAIKF TELAIQRPEH
NINSMYYLGT LYLKNKEITK SGECFKKVLQ QNSEHIPSLI EYATILSLKG EFEKSKKYFK
IALSKDPNNL ICNLRLGKIY LNKLNNINRA IDCFKQIISI EPKYSKAHFQ LGMAYQSRKD
FKLAAECFKQ CISINPNNAD AWQQLGTIFQ ETGNTEKALM YFQKGLVFNP NDFQLQKGIA
NCYYFTENYD TAIEKYENLL KNKQDDEALQ YLADCYYTKD DVENAIYYYK QCLEINPKRP
NCLYNLGNAY CTQNNYEEAQ QAYIECIQLD TTNASAYYNL ANVYYIQNDY ENALINFELA
IEKDPSNVEW RNYIAGLYID NNQFDKAIQH LLKAYDDGTS NFDTCFKLAQ AYYGQQNLSE
ARQYIKVAVE IDPDNDDAYR LYEELNPAPV NKSNSQNKDS NVSASKDLES DASQIKYSQA
SIQVFKENMD LSIRQERNGK SYNKGSQSRI LKENIE
//
