ID I7M898_TETTS Unreviewed; 435 AA.
AC I7M898;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Alpha/beta hydrolase family protein {ECO:0000313|EMBL:EAR97438.2};
GN ORFNames=TTHERM_00340190 {ECO:0000313|EMBL:EAR97438.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR97438.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662666; EAR97438.2; -; Genomic_DNA.
DR RefSeq; XP_001017683.2; XM_001017683.2.
DR AlphaFoldDB; I7M898; -.
DR STRING; 312017.I7M898; -.
DR GeneID; 7828086; -.
DR KEGG; tet:TTHERM_00340190; -.
DR eggNOG; KOG1552; Eukaryota.
DR InParanoid; I7M898; -.
DR OrthoDB; 180696at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR001375; Peptidase_S9.
DR PANTHER; PTHR12277; ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12277:SF204; ALPHA_BETA HYDROLASE DOMAIN-CONTAINING PROTEIN AHO-3; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:EAR97438.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 104..215
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT DOMAIN 234..303
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT COILED 392..419
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 435 AA; 50855 MW; 0B5E1FFF6F027CAA CRC64;
MECILKLFLC LSKCGLRDCL IKQVAFLPPK EKYTLEPDVA RIYGDSKLIQ TYKMRRLKIP
KQKQGNVYEY LPSHKNMETH VFCIGQNQIP AILCRNLQSK KNKILLCSHG NSTDLSQYYD
FLCELSQELE CDTFCYEYPG YGPTPGKLSD KYIIENIECA YDFITSTLEY TWQNIILYSH
SLGSGPSIFL ASQNQKPIGG MILNSPLSSG LKLLLPNNTI TAKEDFFPNF QMIKFVNCPV
FIMHGDKDDI IPIKHGKYLY KKLKQNSKYN PWWVKDANHN DIQYNNRQEF FERISNFLKY
CSNFSLNKTE KDMRADEWGN KFNHLYADWK QDKKNINQRR TVKSQSVISA SQFNTTVKDD
QKSQKYQYED ENIPPISNKN KSEITLSNYN IKNSEKMKKK DLKSEIAQYQ QQYSEILKKG
DPELQSSHFK IKKIQ
//
