ID I7MAY3_TETTS Unreviewed; 381 AA.
AC I7MAY3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Amine-terminal domain alanine racemase {ECO:0000313|EMBL:EAS06717.1};
GN ORFNames=TTHERM_00688570 {ECO:0000313|EMBL:EAS06717.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS06717.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SIMILARITY: Belongs to the DSD1 family.
CC {ECO:0000256|ARBA:ARBA00005323}.
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DR EMBL; GG662260; EAS06717.1; -; Genomic_DNA.
DR RefSeq; XP_001026959.1; XM_001026959.3.
DR AlphaFoldDB; I7MAY3; -.
DR STRING; 312017.I7MAY3; -.
DR EnsemblProtists; EAS06717; EAS06717; TTHERM_00688570.
DR GeneID; 7844007; -.
DR KEGG; tet:TTHERM_00688570; -.
DR eggNOG; ENOG502QRZ0; Eukaryota.
DR HOGENOM; CLU_031639_2_2_1; -.
DR InParanoid; I7MAY3; -.
DR OMA; WPRFYGW; -.
DR OrthoDB; 5473289at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProt.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR Gene3D; 2.40.37.20; D-serine dehydratase-like domain; 1.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR026956; D-ser_dehydrat-like_dom.
DR InterPro; IPR042208; D-ser_dehydrat-like_sf.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR28004:SF2; D-SERINE DEHYDRATASE; 1.
DR PANTHER; PTHR28004; ZGC:162816-RELATED; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR Pfam; PF14031; D-ser_dehydrat; 1.
DR SMART; SM01119; D-ser_dehydrat; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 256..364
FT /note="D-serine dehydratase-like"
FT /evidence="ECO:0000259|SMART:SM01119"
SQ SEQUENCE 381 AA; 42783 MW; A3BF90876BE98AAB CRC64;
MLGNFLDTIT IPSPVVNPNI IRENVMRMKK KIESFNANFR PHFKTHQCAY VGTIVRECGV
NQIAVSSVSM AFYFAKNGWK DITLAIPFNI RELKPLLQLA QKIDVLNIMI DHEQTAQYVA
EHVQDAKLGI FFKIDTGYKR CGVQPQEYEA VDKLLSIIGQ NNNLTFKGFL THCGHTYQKT
TCEERQEILE GAREAMIALR ARYITKFPKI IISVGDTPGI SAAKNLEGID EVRPGNYVFF
DVMQARMNNC EAKNISITVA CPIISLHPER KQIVVYGGGT HLSKEYLVSE QGQKICGWVV
KYNKDGTWTH LPNALVTTLS QEHGIITFEN ASDLDQYKIG DVIGMLPVHS CMTSCVSKFM
YSTDGTKHGT LLGETEDYPS F
//
