ID I8QZ15_9THEO Unreviewed; 302 AA.
AC I8QZ15;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Ribose 5-phosphate isomerase B {ECO:0000313|EMBL:EIW00363.1};
GN ORFNames=ThesiDRAFT1_1425 {ECO:0000313|EMBL:EIW00363.1};
OS Thermoanaerobacter siderophilus SR4.
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacter.
OX NCBI_TaxID=880478 {ECO:0000313|EMBL:EIW00363.1};
RN [1] {ECO:0000313|EMBL:EIW00363.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SR4 {ECO:0000313|EMBL:EIW00363.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Pagani I., Hemme C., Woyke T.;
RT "Improved High-Quality Draft sequence of Thermoanaerobacter siderophilus
RT SR4.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the LacAB/RpiB family.
CC {ECO:0000256|ARBA:ARBA00008754}.
CC -!- SIMILARITY: Belongs to the low molecular weight phosphotyrosine protein
CC phosphatase family. {ECO:0000256|ARBA:ARBA00011063}.
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DR EMBL; CM001486; EIW00363.1; -; Genomic_DNA.
DR AlphaFoldDB; I8QZ15; -.
DR PATRIC; fig|880478.3.peg.2626; -.
DR HOGENOM; CLU_059739_1_0_9; -.
DR Proteomes; UP000005110; Chromosome.
DR GO; GO:0016861; F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses; IEA:UniProt.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd16344; LMWPAP; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.40.1400.10; Sugar-phosphate isomerase, RpiB/LacA/LacB; 1.
DR InterPro; IPR023485; Ptyr_pPase.
DR InterPro; IPR036196; Ptyr_pPase_sf.
DR InterPro; IPR004785; RpiB.
DR InterPro; IPR003500; RpiB_LacA_LacB.
DR InterPro; IPR036569; RpiB_LacA_LacB_sf.
DR InterPro; IPR017867; Tyr_phospatase_low_mol_wt.
DR NCBIfam; TIGR01120; rpiB; 1.
DR NCBIfam; TIGR00689; rpiB_lacA_lacB; 1.
DR PANTHER; PTHR43732:SF1; RIBOSE 5-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR43732; RIBOSE 5-PHOSPHATE ISOMERASE-RELATED; 1.
DR Pfam; PF02502; LacAB_rpiB; 1.
DR Pfam; PF01451; LMWPc; 1.
DR PRINTS; PR00719; LMWPTPASE.
DR SMART; SM00226; LMWPc; 1.
DR SUPFAM; SSF52788; Phosphotyrosine protein phosphatases I; 1.
DR SUPFAM; SSF89623; Ribose/Galactose isomerase RpiB/AlsB; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:EIW00363.1}.
FT DOMAIN 1..145
FT /note="Phosphotyrosine protein phosphatase I"
FT /evidence="ECO:0000259|SMART:SM00226"
FT ACT_SITE 7
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR617867-1"
FT ACT_SITE 13
FT /evidence="ECO:0000256|PIRSR:PIRSR617867-1"
FT ACT_SITE 119
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR617867-1"
SQ SEQUENCE 302 AA; 33312 MW; 76FE2451E67CCD6D CRC64;
MKVLFVCTGN TCRSPMAEGL FNDKAKAFGK DFEAKSAGVF APEGFPASQE AIEVLKQDYN
IDISNHRSKS LRRQDLEEAD LILAMSNSHK QSILSKYPEY SNKVFTIKEF VGLEGEVEDP
YGMPIEVYRE TARELEDLIS KIITKISQER KGKMVIALGA DHGGYELKEA IKKYLNEKGI
AYKDFGTFST ESVDYPDYAL KVAEAVASHE CSEGILVCGT GIGMSIAANK VPGIRAAHAE
DVFSAKAAKE HNNANILCLG GRITGPGLAV MMVEEWLNAT FQGGRHQRRI DKIAEIEKKY
SK
//
