ID I9ACL0_9BACE Unreviewed; 329 AA.
AC I9ACL0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Arabinan endo-1,5-alpha-L-arabinosidase A {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1074_03014 {ECO:0000313|EMBL:EIY85455.1};
OS Bacteroides xylanisolvens CL03T12C04.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=997892 {ECO:0000313|EMBL:EIY85455.1};
RN [1] {ECO:0000313|EMBL:EIY85455.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL03T12C04 {ECO:0000313|EMBL:EIY85455.1};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides xylanisolvens CL03T12C04.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIY85455.1}.
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DR EMBL; AGXE01000016; EIY85455.1; -; Genomic_DNA.
DR RefSeq; WP_008024227.1; NZ_JH724295.1.
DR AlphaFoldDB; I9ACL0; -.
DR PATRIC; fig|997892.3.peg.3093; -.
DR HOGENOM; CLU_009397_4_2_10; -.
DR Proteomes; UP000003566; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd18827; GH43_XlnD-like; 1.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR43772; ENDO-1,4-BETA-XYLANASE; 1.
DR PANTHER; PTHR43772:SF7; PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04480)-RELATED; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00022651};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00022651};
KW Signal {ECO:0000256|SAM:SignalP};
KW Xylan degradation {ECO:0000256|ARBA:ARBA00022651}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..329
FT /note="Arabinan endo-1,5-alpha-L-arabinosidase A"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003718609"
FT SITE 159
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 329 AA; 37099 MW; 806FAF27CFA6E14B CRC64;
MKLKHLILLS IICCSQSVFG QKANQQPKTS GNPVFPGWYA DPEGVVFGDE YWIYPTYSAP
YDEQTFMDAF SSKDLVNWTK HPKVLSKENI SWFKRALWAP AVIHANDKYY IFFGANDIQS
NNELGGIGVA VADNPAGPFK DALGKPLIDK FVNGAQPIDQ FVYKDDDGQY YMYYGGWGHC
NMVKLAPDLL SIVPFEDGTL YKEVTPEKYV EGPFMLKRNG KYYFMWSEGG WTGPDYCVAY
AIADSPFGPF KREAKILQRD PNIGTGAGHH SVVKGPGEDE WYIIYHRHPL GETDGNARVT
CVDRMYFDKD GKIKPIKMTF EGVKASPLK
//
