ID I9QB24_HELPX Unreviewed; 245 AA.
AC I9QB24;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=DNA transformation competence protein ComB8 {ECO:0000313|EMBL:EJB31746.1};
GN Name=comB8 {ECO:0000313|EMBL:EJB31746.1};
GN ORFNames=HPNQ4099_0141 {ECO:0000313|EMBL:EJB31746.1};
OS Helicobacter pylori NQ4099.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992026 {ECO:0000313|EMBL:EJB31746.1, ECO:0000313|Proteomes:UP000003402};
RN [1] {ECO:0000313|EMBL:EJB31746.1, ECO:0000313|Proteomes:UP000003402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NQ4099 {ECO:0000313|EMBL:EJB31746.1,
RC ECO:0000313|Proteomes:UP000003402};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJB31746.1}.
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DR EMBL; AKNU01000001; EJB31746.1; -; Genomic_DNA.
DR RefSeq; WP_001208404.1; NZ_AKNU01000001.1.
DR AlphaFoldDB; I9QB24; -.
DR PATRIC; fig|992026.3.peg.135; -.
DR Proteomes; UP000003402; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd16424; VirB8; 1.
DR Gene3D; 3.10.450.230; VirB8 protein; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR007430; VirB8.
DR Pfam; PF04335; VirB8; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..239
FT /note="Bacterial virulence protein VirB8"
FT /evidence="ECO:0000259|Pfam:PF04335"
SQ SEQUENCE 245 AA; 28611 MW; 0BF0AEF962D3950E CRC64;
MREKPFNSEQ LIYLEELLSH QEKHLENKLS GFSVNDLDMQ SVFRLERNRL KIAYRLLGLM
SFIVLVLAIV LISILPLQKT EHHFVDFLNQ DKHYAIIQRA DKSISSNEAL ARSLIGAYVL
NRESINRIDD KSRYELVRLQ SSSKVWQRFE DLIKTQNSIY AQSHLEREVH IVNIAIYQQD
NNPIASVSIA AKLLNENKLV YEKRYKIVLS YLFDTPDFDY ASMPKNPTGF KITRYSITEI
TNRGD
//
