ID   I9S7Y6_9BACE            Unreviewed;       729 AA.
AC   I9S7Y6;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   SubName: Full=Glutamine synthetase {ECO:0000313|EMBL:EIY51826.1};
GN   ORFNames=HMPREF1068_01373 {ECO:0000313|EMBL:EIY51826.1};
OS   Bacteroides nordii CL02T12C05.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=997884 {ECO:0000313|EMBL:EIY51826.1, ECO:0000313|Proteomes:UP000003089};
RN   [1] {ECO:0000313|EMBL:EIY51826.1, ECO:0000313|Proteomes:UP000003089}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CL02T12C05 {ECO:0000313|EMBL:EIY51826.1,
RC   ECO:0000313|Proteomes:UP000003089};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA   Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA   Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA   Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Bacteroides nordii CL02T12C05.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC       {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EIY51826.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AGXS01000015; EIY51826.1; -; Genomic_DNA.
DR   RefSeq; WP_002559557.1; NZ_JH724314.1.
DR   AlphaFoldDB; I9S7Y6; -.
DR   STRING; 997884.HMPREF1068_01373; -.
DR   GeneID; 69501036; -.
DR   PATRIC; fig|997884.3.peg.1397; -.
DR   eggNOG; COG3968; Bacteria.
DR   HOGENOM; CLU_024307_0_0_10; -.
DR   Proteomes; UP000003089; Unassembled WGS sequence.
DR   GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR   GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.20.120.1560; -; 1.
DR   Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR   InterPro; IPR040577; Gln-synt_C.
DR   InterPro; IPR008147; Gln_synt_N.
DR   InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR   InterPro; IPR008146; Gln_synth_cat_dom.
DR   InterPro; IPR027303; Gln_synth_gly_rich_site.
DR   InterPro; IPR022147; GSIII_N.
DR   PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR   PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR   Pfam; PF00120; Gln-synt_C; 1.
DR   Pfam; PF18318; Gln-synt_C-ter; 1.
DR   Pfam; PF12437; GSIII_N; 1.
DR   SMART; SM01230; Gln-synt_C; 1.
DR   SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR   PROSITE; PS00181; GLNA_ATP; 1.
DR   PROSITE; PS51986; GS_BETA_GRASP; 1.
DR   PROSITE; PS51987; GS_CATALYTIC; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000003089}.
FT   DOMAIN          85..174
FT                   /note="GS beta-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS51986"
FT   DOMAIN          179..615
FT                   /note="GS catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51987"
SQ   SEQUENCE   729 AA;  82544 MW;  C329DE585C36916E CRC64;
     MSKMRFLALQ ELSSRCPLEI TPPSNKLSDY YGSHVFDRKK MQEYLPKEAY KAVMDAIEKG
     TPINREMADL IANGMKSWAK SLNVTHYTHW FQPLTDGTAE KHDGFIEFSE DGGVIERFSG
     KLLIQQEPDA SSFPNGGIRN TFEARGYTAW DVSSPAFVVD TTLCIPTIFI SYTGEALDYK
     TPLLKALAAV DKAATEVCQL FDKNITRVFT NLGWEQEYFL VDSSLYNARP DLCLTGRTLM
     GHSSAKDQQL EDHYFGSIPP RVTAFMKELE IECHKLGIPA KTRHNEVAPN QFELAPIFEN
     ANLANDHNQL VMDLMKRIAR KHHFAVLLHE KPYSGVNGSG KHNNWSLCTD TGINLFAPGK
     NPKGNMLFLT FLVNVLMMVY KNQDLLRASI MSAGNSHRLG ANEAPPAILS IFLGRQLSST
     LDEIVRQVGS SKMTPEEKTT LKLGIGRIPE ILLDTTDRNR TSPFAFTGNR FEFRAAGSSS
     NCAAAMIAIN AAMANQLNEF RASVEKLMEE GIGKDEAIFR LLKETIIASE PIRFEGDGYS
     EEWKQEAARR GLTNICHVPE ALMHYVDNQS KSVLIGERIF NETELACRLE VELEKYTMKV
     QIESRVLGDL AINHIVPIAV SYQNRLLENL LGMKEIFSPE EYEVMSADRK ELIKEISRRV
     TAIKVLVRDM TEARKVANHK ENFQEKAFAY EETVRPYLES IRDHIDHLEM EIDDEIWPLP
     KYRELLFTK
//