ID I9URQ6_9BACE Unreviewed; 794 AA.
AC I9URQ6;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=DUF2264 domain-containing protein {ECO:0000259|Pfam:PF10022};
GN ORFNames=HMPREF1074_03494 {ECO:0000313|EMBL:EIY85243.1};
OS Bacteroides xylanisolvens CL03T12C04.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=997892 {ECO:0000313|EMBL:EIY85243.1, ECO:0000313|Proteomes:UP000003566};
RN [1] {ECO:0000313|EMBL:EIY85243.1, ECO:0000313|Proteomes:UP000003566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL03T12C04 {ECO:0000313|EMBL:EIY85243.1,
RC ECO:0000313|Proteomes:UP000003566};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides xylanisolvens CL03T12C04.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 88 family.
CC {ECO:0000256|ARBA:ARBA00038358}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIY85243.1}.
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DR EMBL; AGXE01000018; EIY85243.1; -; Genomic_DNA.
DR RefSeq; WP_008024942.1; NZ_JH724296.1.
DR AlphaFoldDB; I9URQ6; -.
DR PATRIC; fig|997892.3.peg.3588; -.
DR HOGENOM; CLU_017347_0_0_10; -.
DR Proteomes; UP000003566; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR049349; DUF2264_N.
DR InterPro; IPR010905; Glyco_hydro_88.
DR PANTHER; PTHR36845; HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED; 1.
DR PANTHER; PTHR36845:SF1; UNSATURATED CHONDROITIN DISACCHARIDE HYDROLASE-RELATED; 1.
DR Pfam; PF10022; DUF2264; 1.
DR Pfam; PF07470; Glyco_hydro_88; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..794
FT /note="DUF2264 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005685248"
FT DOMAIN 416..775
FT /note="DUF2264"
FT /evidence="ECO:0000259|Pfam:PF10022"
FT ACT_SITE 120
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR610905-1"
FT ACT_SITE 178
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR610905-1"
FT BINDING 120
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610905-2"
FT BINDING 178
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610905-2"
FT BINDING 238
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610905-2"
FT BINDING 250
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610905-2"
FT BINDING 254
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610905-2"
SQ SEQUENCE 794 AA; 90388 MW; AAC13317B2A7DF98 CRC64;
MVMKIRKRIL IISLTLLAGF TCSAGAVTKG MKKVIDDALD FSVKQSMSMF NEMKDQKGIL
PRTAENGKMI TCESAWWTSG FYPGTLWYCY EYSNDPQIRA AAEEMTSRVE KQKYTTSNHD
VGFIINCSFG NGYRLTHNET YRKVIETAAK SLSTRFHPVT GCTRSWNSKK WQFSVIIDNM
MNLELLNVAS SLTGDNTYYN MAKSHADRTM INHFRPDGSS YHVVSYDTIT GKVLNQVTHQ
GVNDQSSWSR GQAWGLYGFT MMYRQTGKKE YLDHAIKIGK FIMNHPRLPK DKIPYWDFDA
PNIPKEDRDA SAGAIMASAY VELSTYVEGE LSKQFLTIAE QQIKSLASPA YRAKKVGDNN
HYIIKHCTGF MAKQYEIDAP LTYADYYFIE ALIRYKKLLE NRPVVETITA FSENSDRSLW
LSSLHRISYP LLTNMAKGEL RKNMPVESIA ADMQKRKEVT HLEALGRLIT GISTWLELGP
DNTIEGKLRA EYIDLALKSI SNGVNPQSPD YLNFNNGRQP LVDAAFLAHG LLRARTQLWD
KLDKTTQERV IKELKSSRVI KPSETNWLFF SAMVEAALKE FTGEWEYERV KYACDRFAQW
YKGDGWYGDG TDFHLDYYNS FVIHPMMVEV LEIMKKNGIE SSIPYDLELE RYARYAEQQE
RLISPEGTFP IVGRSLAYRF GAFHALSDVA YRKLLPERVK PAQVRSALSA IINRQVNAPG
TFNPEGWLRV GFAGYQPHIG ETYISTGSLY LCTAVFIALG LPESDEFWSS PSADWTCKKG
WAGVDLNVDK ALKK
//
