ID I9W087_HELPX Unreviewed; 434 AA.
AC I9W087;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Flagellum-specific ATP synthase {ECO:0000313|EMBL:EJB97484.1};
DE EC=3.6.3.14 {ECO:0000313|EMBL:EJB97484.1};
GN Name=fliI {ECO:0000313|EMBL:EJB97484.1};
GN ORFNames=HPHPP2_1712 {ECO:0000313|EMBL:EJB97484.1};
OS Helicobacter pylori Hp P-2.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992073 {ECO:0000313|EMBL:EJB97484.1, ECO:0000313|Proteomes:UP000004326};
RN [1] {ECO:0000313|EMBL:EJB97484.1, ECO:0000313|Proteomes:UP000004326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hp P-2 {ECO:0000313|EMBL:EJB97484.1,
RC ECO:0000313|Proteomes:UP000004326};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + cellular proteinSide 1 = ADP + phosphate +
CC cellular proteinSide 2.; EC=7.4.2.8;
CC Evidence={ECO:0000256|ARBA:ARBA00034006};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJB97484.1}.
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DR EMBL; AKPJ01000006; EJB97484.1; -; Genomic_DNA.
DR RefSeq; WP_001128734.1; NZ_AKPJ01000006.1.
DR AlphaFoldDB; I9W087; -.
DR PATRIC; fig|992073.3.peg.1660; -.
DR Proteomes; UP000004326; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030257; C:type III protein secretion system complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-EC.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:UniProtKB-EC.
DR GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR CDD; cd18114; ATP-synt_flagellum-secretory_path_III_C; 1.
DR CDD; cd01136; ATPase_flagellum-secretory_path_III; 1.
DR Gene3D; 3.40.50.12240; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR020003; ATPase_a/bsu_AS.
DR InterPro; IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
DR InterPro; IPR005714; ATPase_T3SS_FliI/YscN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR040627; T3SS_ATPase_C.
DR NCBIfam; TIGR01026; fliI_yscN; 1.
DR PANTHER; PTHR15184; ATP SYNTHASE; 1.
DR PANTHER; PTHR15184:SF9; SPI-1 TYPE 3 SECRETION SYSTEM ATPASE; 1.
DR Pfam; PF00006; ATP-synt_ab; 1.
DR Pfam; PF18269; T3SS_ATPase_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00152; ATPASE_ALPHA_BETA; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:EJB97484.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 156..337
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 434 AA; 47605 MW; AE2F85573404F250 CRC64;
MPLKSLKNRL NQHFDLSPRY GSVKKIMPNI VYADGFNPSV GDVVKIEKSD GSECVGMVVV
AEKEQFGFTP FNFVEGARAG DKVLFLKEGL NFPVGRNLLG RVLNPLGQVI DNKGALDYER
LAPVITTPIA PLKRGLIDEV FSVGVKSIDG LLTCGKGQKL GIFAGSGVGK STLMGMITRG
CLAPIKVIAL IGERGREIPE FIEKNLKGDL SSCVLVVATS DDSPLMRKYG AFCAMSVAEY
FKNQGLDVLF IMDSVTRFAM AQREIGLALG EPPTSKGYPP SALSLLPQLM ERAGKEENKG
SITAFFSVLV EGDDLSDPIA DQARSILDGH IVLSRELTDY GIYPPINILN SASRVAKDII
SESQNLCARK FRRLYALLKE NEMLIRIGSY QMGNDKELDE AIKKKALMEQ FLAQDENALQ
PFEQSFQQLE EILR
//
