ID J0D924_AURST Unreviewed; 734 AA.
AC J0D924;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Acid protease {ECO:0000313|EMBL:EJD36256.1};
GN ORFNames=AURDEDRAFT_174647 {ECO:0000313|EMBL:EJD36256.1};
OS Auricularia subglabra (strain TFB-10046 / SS5) (White-rot fungus)
OS (Auricularia delicata (strain TFB10046)).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Auriculariales; Auriculariaceae; Auricularia.
OX NCBI_TaxID=717982 {ECO:0000313|EMBL:EJD36256.1, ECO:0000313|Proteomes:UP000006514};
RN [1] {ECO:0000313|Proteomes:UP000006514}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TFB10046 {ECO:0000313|Proteomes:UP000006514};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447, ECO:0000256|RuleBase:RU000454}.
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DR EMBL; JH687866; EJD36256.1; -; Genomic_DNA.
DR RefSeq; XP_007355610.1; XM_007355548.1.
DR AlphaFoldDB; J0D924; -.
DR KEGG; adl:AURDEDRAFT_174647; -.
DR eggNOG; KOG1339; Eukaryota.
DR InParanoid; J0D924; -.
DR OrthoDB; 1697158at2759; -.
DR Proteomes; UP000006514; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR PANTHER; PTHR47966; BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR47966:SF92; PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00026; Asp; 1.
DR PRINTS; PR00792; PEPSIN.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
PE 3: Inferred from homology;
KW Aspartyl protease {ECO:0000256|ARBA:ARBA00022750,
KW ECO:0000256|RuleBase:RU000454}; Hydrolase {ECO:0000256|RuleBase:RU000454};
KW Protease {ECO:0000256|RuleBase:RU000454, ECO:0000313|EMBL:EJD36256.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006514}.
FT DOMAIN 318..647
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
SQ SEQUENCE 734 AA; 78530 MW; 9EC25C9A3A429872 CRC64;
MITPSYLELS QADRASPPAG IKIMLGGEEG AAALLADLSA TPCKIPNDWI SSVGSLECYS
DESNLTVATL LRLCSRLPQL RVLDLCNLQA PLDDFPGLIN SIMRSNAFEN VTHCVLGSYA
PGATPLTAAY AIISSMRKVQ RVELDMFAFP WQEAERERIQ NLGLAHVRLR SYTCAAFFFR
CALPIVDSAD TLEHLEIILD DKWHTNIANK FASALRTRSF VRLRALDVFN EANAFQYRGT
MTEAIQSIFK ECPNLPLLPA VFIAVSFLHT AAGARLSARE LSTTPGIRFT TLARRAPDDK
LPTSPKGIRA GNFENTAYVG NLTLGSKSFL VQLDTGSSDL WVDHGSQTIE QLGGDSIPGA
PRVKMSYALG SVDGTPVYGD VSLGDYHSQK QLMLSADGAA NLEALKKYGI SGILGLGLDG
GALIPTILTG EDAEAHSFLG NIFAQNASAG SFTTWYLGRD GDGLMTINEL PESYAEPIKA
APEIIVHSPL AGDIPRWAIE VASIEVGGKK TDLISELTGG TTRAIAVVDT GATLSFIPKE
ITDLIYSGVP GAKYASTVGV WVVPCTASID VAFTIGRTRY FVDPLDVLSR PAEIKIGGKA
ASVCIGGFIP APAALQQQLE LDLLLGDNFL RNVFSVLHYN TPSMQLLSVT DETEAKAQFA
GLRDETMKAF PPEVDLTDEK TFNDVVSALG ANPLGDDPGS SSGDGNSVSD AATHLTSWNA
PVLIVLFSVV MFLL
//
