ID J0KJR3_HELPX Unreviewed; 328 AA.
AC J0KJR3;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Bacterial virulence protein VirB8 domain-containing protein {ECO:0000259|Pfam:PF04335};
GN ORFNames=HPHPH24_1311 {ECO:0000313|EMBL:EJB50912.1};
OS Helicobacter pylori Hp H-24.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992039 {ECO:0000313|EMBL:EJB50912.1, ECO:0000313|Proteomes:UP000004761};
RN [1] {ECO:0000313|EMBL:EJB50912.1, ECO:0000313|Proteomes:UP000004761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hp H-24 {ECO:0000313|EMBL:EJB50912.1,
RC ECO:0000313|Proteomes:UP000004761};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJB50912.1}.
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DR EMBL; AKOG01000006; EJB50912.1; -; Genomic_DNA.
DR RefSeq; WP_000409342.1; NZ_AKOG01000006.1.
DR AlphaFoldDB; J0KJR3; -.
DR PATRIC; fig|992039.3.peg.1271; -.
DR Proteomes; UP000004761; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd16424; VirB8; 1.
DR Gene3D; 3.10.450.230; VirB8 protein; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR007430; VirB8.
DR Pfam; PF04335; VirB8; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 101..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 105..287
FT /note="Bacterial virulence protein VirB8"
FT /evidence="ECO:0000259|Pfam:PF04335"
SQ SEQUENCE 328 AA; 37951 MW; 84AB78368C5A3CE5 CRC64;
MEKACMNAWG LPKVLEERLK EKYGDDWEKY VKAKAISEEE LEEQVKDKAK EQQKTQREKT
LSGFLKKVGL KKRDMLQSTM LFDGVKEADV LFQAERKIGD WIFSSAVFFF ALALIEAIII
VCLLPLKEKV PYLVTFSNAT QNFAIVQRAD KSIRANQALV RQLVASYVNN RENISSIKEQ
NEIAHETIRL QSAFEVWDFF EKLVSYEHSI YTNVNLTRKI SIINIALISK TQANIEISAQ
LFNKEKLESK KRYRIIMTFE FEPIEIDTKS VPLNPTGFIV TGYDVTEIAI LKDLDEKNKV
KDDGVKSRII HVEKKDPHMS QYKDVKEQ
//
