ID   J0NIQ5_9ACTO            Unreviewed;      1769 AA.
AC   J0NIQ5;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Putative 2-hydroxyglutaryl-CoA dehydratase, D-component {ECO:0000313|EMBL:EJF46999.1};
GN   ORFNames=HMPREF1318_2217 {ECO:0000313|EMBL:EJF46999.1};
OS   Actinomyces massiliensis F0489.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC   Actinomyces.
OX   NCBI_TaxID=1125718 {ECO:0000313|EMBL:EJF46999.1, ECO:0000313|Proteomes:UP000002941};
RN   [1] {ECO:0000313|EMBL:EJF46999.1, ECO:0000313|Proteomes:UP000002941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0489 {ECO:0000313|EMBL:EJF46999.1,
RC   ECO:0000313|Proteomes:UP000002941};
RA   Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA   Nelson K.E.;
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJF46999.1}.
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DR   EMBL; AKFT01000036; EJF46999.1; -; Genomic_DNA.
DR   PATRIC; fig|1125718.3.peg.565; -.
DR   eggNOG; COG1924; Bacteria.
DR   eggNOG; COG3580; Bacteria.
DR   eggNOG; COG3581; Bacteria.
DR   Proteomes; UP000002941; Unassembled WGS sequence.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR002731; ATPase_BadF.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018709; CoA_activase_DUF2229.
DR   PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR   PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   Pfam; PF01869; BcrAD_BadFG; 2.
DR   Pfam; PF09989; DUF2229; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002941}.
FT   DOMAIN          12..312
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          441..695
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          792..1026
FT                   /note="DUF2229"
FT                   /evidence="ECO:0000259|Pfam:PF09989"
FT   REGION          360..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1060..1092
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1178..1220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1234..1291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1706..1769
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1060..1074
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1710..1724
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1769 AA;  187484 MW;  4169EC31281DC3AF CRC64;
     MPAPAGAQPV SLGLDVGSTT VKLVLLPDSC AVPAPVAPQA ALLPDSCAVP APVAPQAALL
     PEPSAVPAPA GVSGGSDAAP APLFAEYRRH NADVRGEVTR LLAEAAERFP NATVRGAVTG
     SAGLSLATLM GLPFVQEVIA ETRTVQAKNP EADVIIELGG EDAKITYLHP TPEQRMNGTC
     AGGTGAFIDQ MAQLLHTDAP GLNELAAAHT TLYPIASRCG VFAKSDLQPL INQGAEPADL
     AASVLQAVVT QTIAGLACGR PIRGNVMFLG GPLHFLSELR GAFERTLADQ VDSFTCPGDA
     QLYVAVGAAL MASGQPVTLA ELSTRLATRK SLSLATSRMR PLFSDDDELA AFRERHARAT
     IPRTGWPEPP AASVAQSPDD VDDPASAVES AADGAHCDPT ADSAAAVGTT GPDAVGEDVG
     GPDPAESSES ADAAPRVDCF LGIDAGSTTI KAVVLDEAGN IAWEHYAGNE GDPVTAAVEI
     LRRIHLEMPD HVRIVRSCVT GYGESIVKAA LHIDEGVVET MAHYRAAARL NPEVTSVIDI
     GGQDMKYLRI RGGAIDSISV NEACSAGCGS FLQTFAQSMG QTVQEFAEEA LRAERPVDLG
     SRCTVFMNSS VKQAQKESAT PGEISAGLSY SVVRNALYKV IKLRDADQLG DYVSVQGGTF
     LNDAVLRAFE LLTGREVVRP DVAGLMGCLG AALTARETYD GVPSTLMTLA ELSRFSLTTE
     TSVCKLCQNH CKLTITTFGD GQRHVSGNRC ERGATQERRA KKSDMPNLYD YKYRRTFAYR
     RLRRGQDTRG EIGVPRVLGM YENYPLWFTI LTQLGFRVMI SGRSNHELFE SGMDSIPSEN
     VCYPAKLAHG HVKSLIDKGV KTIWFPCVFF ERKLVDRADD HFNCPIVATY PEVIRTNVEQ
     LRGGRGGTGD AEGADGAEGA GVRMLSPFLN LANPGKLAER LVEVFADWDV TLPEARKAVA
     AGFAEDAAFK ADVRAEGRRT LEWMHEHGRK GIVLAGRPYH IDPEINHGVP DVINTLGMAV
     LSEDSILPEP ARPEVEADDG VEHQVAGGAL SRAVASIRRG LSRKKEDPQA PADWSDVRAE
     DLPSPEASVA TESSAVHLRV RDQWAYHSRL YQAAELVTDA DDLELVQLNS FGCGVDAVTT
     DQVQEILESA GGVYTTLKID EVSNLGAATI RLRSLSAASE ARRRHRDSAP AAGPGQSGGS
     DARSTGSGAG PVGSDAQAAA RPLENEPVEI DTSLAPAPAA GPAGTASNSA CEGAEPASVG
     ASAGSETEGA GSGGGRPGAR RARELPGATT PAFTEEMRAT HTILMPQMSP VHFRPLAPLM
     RRLGYKVELL ESASRDDLEV GLRYVNNDAC FPAIMVIGQL IGAFEDGTHD PDRCVVAISQ
     TGGMCRATNY AAMLRKGLRD AGYPQIPVLA VSVQGLEENP GFKITPTLAL KVVQGVIIGD
     TLNTCLLRVR PYEAEEGAAN RLLGRWNAII GEFFEHKGRS ATWGGRLGYR RLLREMVREF
     AALPRRDIPR KPRVGVVGEV LVKFQPDANN HVVDQIEAEG CEAVVPGLLA FFVNGPATAQ
     WEADTYGIGL DSLTKKKAAV WFLEQAQAPA RAALAAGRIF DVEASSAVMA QKASKILSLG
     NQAGEGWLLA AEMIELIENG APNIVCCQPF GCLPNHVIGK GMFREIRRQY PQANIVGIDY
     DPGASEVNQL NRLKLMISTA HMIHESQAEE ASSHAGSAGS AESADSAGSA MGEMSELLAD
     LGPAPDNTPQ SPDVAAQEAA QEWVDALRK
//