ID J0PAX4_HELPX Unreviewed; 350 AA.
AC J0PAX4;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=tRNA-5-methylaminomethyl-2-thiouridylate-methyltransferase {ECO:0000313|EMBL:EJB95702.1};
DE EC=2.1.1.61 {ECO:0000313|EMBL:EJB95702.1};
GN Name=trmE1 {ECO:0000313|EMBL:EJB95702.1};
GN ORFNames=HPHPH23_0212 {ECO:0000313|EMBL:EJB95702.1};
OS Helicobacter pylori Hp H-23.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992068 {ECO:0000313|EMBL:EJB95702.1, ECO:0000313|Proteomes:UP000003210};
RN [1] {ECO:0000313|EMBL:EJB95702.1, ECO:0000313|Proteomes:UP000003210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hp H-23 {ECO:0000313|EMBL:EJB95702.1,
RC ECO:0000313|Proteomes:UP000003210};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJB95702.1}.
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DR EMBL; AKPG01000001; EJB95702.1; -; Genomic_DNA.
DR RefSeq; WP_000809464.1; NZ_AKPG01000001.1.
DR AlphaFoldDB; J0PAX4; -.
DR PATRIC; fig|992068.3.peg.202; -.
DR Proteomes; UP000003210; Unassembled WGS sequence.
DR GO; GO:0004808; F:tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR11933:SF6; THIL AANH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11933; TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE; 1.
DR Pfam; PF18297; NFACT-R_2; 1.
DR Pfam; PF03054; tRNA_Me_trans; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:EJB95702.1};
KW Transferase {ECO:0000313|EMBL:EJB95702.1}.
SQ SEQUENCE 350 AA; 40089 MW; 1FA830B19B54D398 CRC64;
MKQIKALALF SGGLDSLLSM KLLIDQGIEV TALHFNIGFG GNKDKREYFE NATAQIGAKL
LVCDIREQFF NDVLFKPKYG YGKYFNPCID CHANMFRNAF YKMLELNADF VLSGEVLGQR
PKSQRKEALN QVRKLVREVG EEARFDPILD RTQASGEKPQ FLDELLLRPM SAKLLEPTFM
EKKGFVDREK LLDVSGRGRA RQLQMIKDYG LKYYEKPGGG CLLTDIQVSN KIKNLKEYRE
MVFEDSVIVK IGRYFVLPHN ARLVVARNEE ENHKLDIQHP LMDKIELLGC KGPLSLVDKN
ASKEDKELAG RIALGYAKTS REQAYLIQIG NEKRELYPLD KESSREYLFA
//
