ID J0QP58_HELPX Unreviewed; 375 AA.
AC J0QP58;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=2-oxoglutarate oxidoreductase OorA subunit {ECO:0000313|EMBL:EJC12713.1};
DE EC=1.2.7.3 {ECO:0000313|EMBL:EJC12713.1};
GN Name=oorA {ECO:0000313|EMBL:EJC12713.1};
GN ORFNames=HPHPP23_0971 {ECO:0000313|EMBL:EJC12713.1};
OS Helicobacter pylori Hp P-23.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992083 {ECO:0000313|EMBL:EJC12713.1, ECO:0000313|Proteomes:UP000004970};
RN [1] {ECO:0000313|EMBL:EJC12713.1, ECO:0000313|Proteomes:UP000004970}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hp P-23 {ECO:0000313|EMBL:EJC12713.1,
RC ECO:0000313|Proteomes:UP000004970};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJC12713.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKPR01000002; EJC12713.1; -; Genomic_DNA.
DR RefSeq; WP_001206876.1; NZ_AKPR01000002.1.
DR AlphaFoldDB; J0QP58; -.
DR PATRIC; fig|992083.3.peg.943; -.
DR Proteomes; UP000004970; Unassembled WGS sequence.
DR GO; GO:0047553; F:2-oxoglutarate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR32154:SF14; 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:EJC12713.1}.
FT DOMAIN 14..243
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 275..368
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 375 AA; 41542 MW; F60D647F0AA227AE CRC64;
MREIISDGNE LVAKAAIEVG CRFFGGYPIT PSSDIMHAMS VALPKCGGHF IQMEDEISGI
SVSLGASMSG TKSMTASSGP GISLKVEQIG YSFMAEIPLV IADVMRSGPS TGMPTRVAQG
DVNFLRHPIH GDFKAVALAP ASLEEAYTET VRAFNLAEML MTPVFLLMDE TVGHMYGKVQ
IPDLEEVQKM IINRKEFVGD KKDYKPYGVA QDEPAVLNPF FKGYRYHVSG LHHGPIGFPT
EDAKIGGDLI DRLFHKIESK QDIINENEEM DLEGAEIIII AYGSVSLAVK EALKDYNKES
KQKVGFFRPK TLWPSPAKRL KEIGDKYEKI LVIELNKGQY LEEIERAMQR KVHFFGQANG
RTISPKQIIA KLKEL
//
