ID J0R0E2_HELPX Unreviewed; 414 AA.
AC J0R0E2;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=RNA polymerase sigma-54 factor {ECO:0000313|EMBL:EJC16558.1};
GN Name=rpoN {ECO:0000313|EMBL:EJC16558.1};
GN ORFNames=HPHPP74_1369 {ECO:0000313|EMBL:EJC16558.1};
OS Helicobacter pylori Hp P-74.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=992091 {ECO:0000313|EMBL:EJC16558.1, ECO:0000313|Proteomes:UP000005724};
RN [1] {ECO:0000313|EMBL:EJC16558.1, ECO:0000313|Proteomes:UP000005724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hp P-74 {ECO:0000313|EMBL:EJC16558.1,
RC ECO:0000313|Proteomes:UP000005724};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- SIMILARITY: Belongs to the sigma-54 factor family.
CC {ECO:0000256|ARBA:ARBA00008798}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJC16558.1}.
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DR EMBL; AKPX01000002; EJC16558.1; -; Genomic_DNA.
DR RefSeq; WP_000996402.1; NZ_AKPX01000002.1.
DR AlphaFoldDB; J0R0E2; -.
DR PATRIC; fig|992091.3.peg.1332; -.
DR Proteomes; UP000005724; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.1330; RNA polymerase sigma-54 factor, core-binding domain; 1.
DR InterPro; IPR000394; RNA_pol_sigma_54.
DR InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR InterPro; IPR038709; RpoN_core-bd_sf.
DR NCBIfam; TIGR02395; rpoN_sigma; 1.
DR PANTHER; PTHR32248; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR PANTHER; PTHR32248:SF4; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR Pfam; PF00309; Sigma54_AID; 1.
DR Pfam; PF04963; Sigma54_CBD; 1.
DR Pfam; PF04552; Sigma54_DBD; 1.
DR PIRSF; PIRSF000774; RpoN; 1.
DR PRINTS; PR00045; SIGMA54FCT.
DR PROSITE; PS00717; SIGMA54_1; 1.
DR PROSITE; PS00718; SIGMA54_2; 1.
DR PROSITE; PS50044; SIGMA54_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 69..247
FT /note="RNA polymerase sigma factor 54 core-binding"
FT /evidence="ECO:0000259|Pfam:PF04963"
FT DOMAIN 254..408
FT /note="RNA polymerase sigma factor 54 DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF04552"
SQ SEQUENCE 414 AA; 48315 MW; 89BF7F594FE20394 CRC64;
MAILRANLSP KNKLNATLKG WLPILQSELE DLEEVLKQNA LDNPLIKIEN KRIKNFSDRF
SAKKSSDHLE NFAIASKSLF ETLEAQIIPP LFPTETSQKI AMDIINGLDS EGYFEENIEE
RAKILGVESE VYEKVRQRFS YLNPAGIGTR DVKESFLFQL ESRELDNNEL YEEARKIILN
LEKHHEFSKD FYYEKALKIL KSFKNPPAIE FLEKEIEVIP ELFILEVDNE IIVRLNDESY
PTISLEENRF KDSDYLKDKL KEAKDLIDAL NLRKATIYKI GLMLLEYQYD FFKGKELRPL
KLLDLANEFN HSVSTISRAI SNKYLACERG VFPIKHFFSI ALDNSETSNA VIKDYLLELI
KNEDKKEPLS DAKILELIEE KFHLKMVRRT ITKYRQLLNI ASSSERKRLY LMRA
//
