ID J0X9J9_9ACTO Unreviewed; 334 AA.
AC J0X9J9;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=MobA-like NTP transferase domain protein {ECO:0000313|EMBL:EJF45346.1};
GN ORFNames=HMPREF1318_0934 {ECO:0000313|EMBL:EJF45346.1};
OS Actinomyces massiliensis F0489.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1125718 {ECO:0000313|EMBL:EJF45346.1, ECO:0000313|Proteomes:UP000002941};
RN [1] {ECO:0000313|EMBL:EJF45346.1, ECO:0000313|Proteomes:UP000002941}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0489 {ECO:0000313|EMBL:EJF45346.1,
RC ECO:0000313|Proteomes:UP000002941};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP =
CC diphosphate + UDP-N-acetyl-alpha-D-glucosamine; Xref=Rhea:RHEA:13509,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:46398,
CC ChEBI:CHEBI:57705, ChEBI:CHEBI:57776; EC=2.7.7.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001851};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-
CC acetyl-alpha-D-glucosamine 1-phosphate; Xref=Rhea:RHEA:13725,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288,
CC ChEBI:CHEBI:57776, ChEBI:CHEBI:58516; EC=2.3.1.157;
CC Evidence={ECO:0000256|ARBA:ARBA00000731};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJF45346.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKFT01000098; EJF45346.1; -; Genomic_DNA.
DR RefSeq; WP_008731258.1; NZ_AKFT01000098.1.
DR AlphaFoldDB; J0X9J9; -.
DR PATRIC; fig|1125718.3.peg.1264; -.
DR eggNOG; COG1207; Bacteria.
DR OrthoDB; 9775031at2; -.
DR Proteomes; UP000002941; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd02540; GT2_GlmU_N_bac; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR025877; MobA-like_NTP_Trfase.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR PANTHER; PTHR43584:SF3; BIFUNCTIONAL PROTEIN GLMU; 1.
DR PANTHER; PTHR43584; NUCLEOTIDYL TRANSFERASE; 1.
DR Pfam; PF12804; NTP_transf_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000002941};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EJF45346.1}.
FT DOMAIN 9..137
FT /note="MobA-like NTP transferase"
FT /evidence="ECO:0000259|Pfam:PF12804"
SQ SEQUENCE 334 AA; 34666 MW; 0A1B71D269C2B6EB CRC64;
MASTAPAAVI VMAAGKGTRM RSAIPKVLHT IGGRSLLNHA VTAARGLHPD HLVVVVRHER
DAVVAHLAEV APDAVPADQD EVPGTGRAVA CGLASLPEDL SGPVVVTSGD VPLLDTGTLE
ALLAQHVRRG DAVTLLTTVL DDPTGYGRIV REGNGPDGAV SAIVEQRDAT PEQRAITEIN
AGVYVFDAAH LRRALTTLGT DNDQGEVYLT DVVARAYAEG LSTSALVATD HWLVEGCNDR
SQLAELGAEL NRRTLARWME AGVGVVDPAG TWVDVSVELA RDVTLEPGVL LRGATRIGEG
SHVGAYAILT DVEIPDGAVV APFSQLDGDA PAGP
//
