ID J1L3L8_9EURY Unreviewed; 738 AA.
AC J1L3L8;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Helicase domain-containing protein {ECO:0000313|EMBL:EJG07682.1};
GN ORFNames=Metli_1738 {ECO:0000313|EMBL:EJG07682.1};
OS Methanofollis liminatans DSM 4140.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanofollis.
OX NCBI_TaxID=28892 {ECO:0000313|EMBL:EJG07682.1};
RN [1] {ECO:0000313|EMBL:EJG07682.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4140 {ECO:0000313|EMBL:EJG07682.1};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Lu M., Detter J.C.,
RA Tapia R., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Spring S., Schuler E., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of Methanofollis liminatans DSM 4140.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM001555; EJG07682.1; -; Genomic_DNA.
DR RefSeq; WP_004039497.1; NZ_CM001555.1.
DR AlphaFoldDB; J1L3L8; -.
DR STRING; 28892.Metli_1738; -.
DR HOGENOM; CLU_002513_3_1_2; -.
DR OrthoDB; 9764at2157; -.
DR Proteomes; UP000005095; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd12089; Hef_ID; 1.
DR CDD; cd20075; XPF_nuclease_XPF_arch; 1.
DR Gene3D; 3.40.50.10130; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 1.20.1320.20; hef helicase domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR006166; ERCC4_domain.
DR InterPro; IPR041755; Hef_ID.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR010994; RuvA_2-like.
DR PANTHER; PTHR14025; FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER; 1.
DR PANTHER; PTHR14025:SF20; FANCONI ANEMIA GROUP M PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF02732; ERCC4; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF21210; RNA_helicase_helical; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00891; ERCC4; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00278; HhH1; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EJG07682.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 23..191
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 356..518
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 738 AA; 80328 MW; 04DEF990A9AB5C79 CRC64;
MSHISHPLIR AESLDERRYQ LAIALQALDR HTMVVLPTGL GKTAVALITA ASRLYREGGR
LLVLAPTKPL VEQHLRYFSE RLALPDEGTC AIFTGDTGPD ERTAMWEGAR AIFATPQVIK
NDLIAGRYTL ADVTLMVVDE CHRAVGNYAY VFLARRYHQT ADKPLLLAMT ASPGGDHGKV
EEVMANLGIE GVETRTESDP DVIPYVHERE VEHRQVDLPE DLALAVGDIN ILIDSRLAAL
KRAGFFAPDR SKLSMKALNK INAEIQGRIA QRDTAAFTAA SIYAELMKLR HAVSLAESQG
SRVLAGYLEK LSKEGQSATG TKASQRLAGD PVFQRLCQRS ASWQGELHPK VGLTVALVKE
QVALHPESRT IVFATFRDTV ALLVEALREA GIGAERFVGQ ASRDAEKGLS QKKQIDVLRR
FREGEFPVIV ATSVGEEGLD VPSTDLVVFY EAVPSEIRSI QRKGRTGRSG TGRIVVFTTK
GTADEVYRYV SQQRERSMQK GIRALGGGST GKGQTNFGSF VAAEPEGPSI TVDDRETSSR
VAEVLSDLGL HIALTRLEVG DYAVGDRIVV ERKTVQDFAD TLVDRDLLGQ VRALAAAAPR
PVLIVEGDGD LYAARDIHPN AIRGALAAIT VDMGVAVIRT KSAEETAEML AVLCRREEGE
PGDRRVQTKK TYTTGQEQLE NIVASFPEIG LKGARALLEH FGSVKAVVEA EKDDLTAVKG
VGKKTADSIW ETARRPYG
//
