ID   J2K4S1_9ACTN            Unreviewed;      1071 AA.
AC   J2K4S1;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   SubName: Full=LuxR family transcriptional regulator {ECO:0000313|EMBL:EJJ07813.1};
GN   ORFNames=SU9_06805 {ECO:0000313|EMBL:EJJ07813.1};
OS   Streptomyces auratus AGR0001.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1160718 {ECO:0000313|EMBL:EJJ07813.1};
RN   [1] {ECO:0000313|EMBL:EJJ07813.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AGR0001 {ECO:0000313|EMBL:EJJ07813.1};
RX   PubMed=22965094; DOI=10.1128/JB.01155-12;
RA   Han X., Li M., Ding Z., Zhao J., Ji K., Wen M., Lu T.;
RT   "Genome Sequence of Streptomyces auratus Strain AGR0001, a Phoslactomycin-
RT   Producing Actinomycete.";
RL   J. Bacteriol. 194:5472-5473(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJJ07813.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJGV01000052; EJJ07813.1; -; Genomic_DNA.
DR   AlphaFoldDB; J2K4S1; -.
DR   STRING; 1160718.SU9_06805; -.
DR   PATRIC; fig|1160718.3.peg.1384; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG2197; Bacteria.
DR   eggNOG; COG3899; Bacteria.
DR   HOGENOM; CLU_006850_0_2_11; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          995..1060
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1071 AA;  115906 MW;  FFE117CFCF7FD372 CRC64;
     MTTPTSVTPP ARTPSARPLV HPAPGRAFRP QKSDAGLSDP CAMLGSVETR SVSPVFVGRA
     AELTALGGAL ARIAASGEPQ AVLIGGEAGV GKTRLIEEFS ESARAQGALV ALGGCIEIGS
     EGLPFAPFSA ILHTLNWHLR DELAAAVAGQ EGELARILPE LGETPTEAHD EEIGRARLFE
     LTARLLERLA VHRTLVLVVE DLHWADRSTR ELLAYLLRAL HDANVLLVAT YRSDDIHRRH
     PLRPFLAEID RMRTVRRIEL ARFNRDEVRS QLAGINGSAP EEDTVDRVFK RSEGNAFFVE
     ELARGLADGA LHGLSDPLRD LLLVRVEALP EDAQRVVRTA AEGGSTVEHE LLSAVCQMPE
     DDLIEALRAA VGSNTLVPTQ DGKGYRFRHA LAREAVVDDL LPGERTRLNR RYAQALEANP
     ALVRADVCAA RLASYWYKAH DAAKALPAVL AASVQARRRH AYAEQLRLLD RALELWDDAP
     TEVRHGVRPV DYTEAYPACG CDDDALRFLD LLAEIAVAAR LSGDAERAFT ITKRALRSLR
     GENDPLRRAW FLMQRSRLCQ STGRGNGWED LGTALELVRG LPPSPVHAAV MAHVANWAML
     HEPGPDTYAT AERAVELALS VGDEEAELNS RVTLGSLRVD AGEAEAGLAE LRSALDRAVD
     RGYFSIIGRG HVNLPSVLES IGRSREAVEV TEQGVALATR YGLKDRTSWV LGNRAESLQS
     LGRWQEAGRA AADARRFAQS PRSLALAANR LTHLALDRGD LAEAERELTV TREHYGTHDP
     QPQHTIPIAR HALRIAARQG RLLDARSLFE RALDAGFPPG TQRYAWPLLW SATAAESDAR
     GLPAAEPGRA AVLAGIRQAA KKLPRLLPVW AAYGLAVDAE LRRAEGRETP DAWAEAVAAF
     EPLERPHELA RACYRWAESL LHAGERATAG LQGRTPREAA VLLLAQAHTA AGTMGARPLA
     EEIELLAQRA RLPLPGLIPA TGNGAGRSEA EEPAAPVPSL GLTRREREVL RLVADGRSNR
     QIADALFISP KTASVHVSNI LAKLGVSGRG EAGAVAHRLR LFGEPAPGMP S
//