ID J2U848_9PSED Unreviewed; 398 AA.
AC J2U848;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=3-oxoacyl-(Acyl-carrier-protein) synthase {ECO:0000313|EMBL:EJM88621.1};
GN ORFNames=PMI33_02634 {ECO:0000313|EMBL:EJM88621.1};
OS Pseudomonas sp. GM67.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1144335 {ECO:0000313|EMBL:EJM88621.1, ECO:0000313|Proteomes:UP000007281};
RN [1] {ECO:0000313|EMBL:EJM88621.1, ECO:0000313|Proteomes:UP000007281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GM67 {ECO:0000313|EMBL:EJM88621.1,
RC ECO:0000313|Proteomes:UP000007281};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJM88621.1}.
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DR EMBL; AKJH01000042; EJM88621.1; -; Genomic_DNA.
DR RefSeq; WP_008039907.1; NZ_AKJH01000042.1.
DR AlphaFoldDB; J2U848; -.
DR PATRIC; fig|1144335.3.peg.2549; -.
DR OrthoDB; 9808669at2; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000007281; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF320; BETA-KETOACYL SYNTHASE; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 1..396
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 398 AA; 42133 MW; BCDDFF5CE02B7E3F CRC64;
MTAYLNALGV ICALGRDKHE VARNLFAGDC SGMRSESGWV PERSLPVAAV RGALAPIPAE
LVKQSTRNNQ LLLEAALQIR DDIDQAIQTY GRDRIGVILG TSTSGIDEAS RGLAHYIREH
QFPDYYDYQQ QELGAPANFL ADWLQLSGPA YVISTACTSS ARALMSAQRL LDLGLCDAVL
CGGVDSLCKL TLNGFSALEA VSEQRCNPFS VNRNGINIGE AAVLFLMTKV AGDKQSIALL
GSGASSDAHH ISAPEPTGRG ALQAMRKALG RASLQPEQIG YLNLHGTATQ HNDAMESLAV
SALFPAGVPC SSTKPMTGHT LGAAGALEAA FCWLSLSADN QTHTLPPHVW DGQPDPQLPA
LNWVTPADRL ASIAPRYLMS NSFAFGGNNV SLIIGDAP
//
