ID J2XTI6_9PSED Unreviewed; 295 AA.
AC J2XTI6;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Dihydrodipicolinate synthase/N-acetylneuraminate lyase {ECO:0000313|EMBL:EJN27990.1};
GN ORFNames=PMI35_03186 {ECO:0000313|EMBL:EJN27990.1};
OS Pseudomonas sp. GM78.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1144337 {ECO:0000313|EMBL:EJN27990.1, ECO:0000313|Proteomes:UP000007302};
RN [1] {ECO:0000313|EMBL:EJN27990.1, ECO:0000313|Proteomes:UP000007302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GM78 {ECO:0000313|EMBL:EJN27990.1,
RC ECO:0000313|Proteomes:UP000007302};
RX PubMed=23045501; DOI=10.1128/JB.01243-12;
RA Brown S.D., Utturkar S.M., Klingeman D.M., Johnson C.M., Martin S.L.,
RA Land M.L., Lu T.Y., Schadt C.W., Doktycz M.J., Pelletier D.A.;
RT "Twenty-one genome sequences from Pseudomonas species and 19 genome
RT sequences from diverse bacteria isolated from the rhizosphere and
RT endosphere of Populus deltoides.";
RL J. Bacteriol. 194:5991-5993(2012).
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJN27990.1}.
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DR EMBL; AKJF01000087; EJN27990.1; -; Genomic_DNA.
DR RefSeq; WP_008059396.1; NZ_AKJF01000087.1.
DR AlphaFoldDB; J2XTI6; -.
DR PATRIC; fig|1144337.3.peg.3083; -.
DR OrthoDB; 199953at2; -.
DR Proteomes; UP000007302; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF73; 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365}.
FT ACT_SITE 138
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 167
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 50
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 295 AA; 31760 MW; DFF6A34B043F3A9D CRC64;
MSSATIHGII GYTITPFTAN GENLDLDALG RSIDRLIDGG VHSIAPLGST GEGAYLSDAE
WDQVAEFSIK HVAKRVPTIV SVSDLTTAKA VRRARLAEAH GADVVMVLPT SYWKLSEAQI
LAHYRAIGDS IGVPIMLYNN PATSGTDMSV DLILRIVKGV ENVTMVKEST GDIQRMHQLY
RLGEGQVPFY NGCNPLALEA FAAGAKGWCT AAPNLIPQLN LDLYDAVLAN DLNKARELFY
RQLPLLDFIL KGGLPATIKA GLRQTGLEVG DPRLPVFPLD EAGLSQLQGL LKALR
//
