ID J3K8H8_COCIM Unreviewed; 567 AA.
AC J3K8H8;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=AMP-dependent synthetase/ligase domain-containing protein {ECO:0000259|Pfam:PF00501};
GN ORFNames=CIMG_11779 {ECO:0000313|EMBL:EAS31126.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS31126.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG704912; EAS31126.3; -; Genomic_DNA.
DR RefSeq; XP_001242709.2; XM_001242708.2.
DR AlphaFoldDB; J3K8H8; -.
DR STRING; 246410.J3K8H8; -.
DR GeneID; 24163879; -.
DR KEGG; cim:CIMG_11779; -.
DR VEuPathDB; FungiDB:CIMG_11779; -.
DR InParanoid; J3K8H8; -.
DR OMA; ADWNIYT; -.
DR OrthoDB; 2343197at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43272:SF11; AMP-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43272; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001261}.
FT DOMAIN 142..547
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 567 AA; 60921 MW; A6A8BEC639B864EE CRC64;
MASSESLISK LDSLLAQLLA DWDIYTTGLA TLLVTYVGYV TFFSKDPDAH PFMLARQAAE
APIRQPGESA TLRALDAPHG YPLKAGLGVR DPETPKWSYG RNGDLRDIWR SAVKGSLNQD
GTPKGKRGKI YTVLGKNVEE RSIDEISKEI NVLGQYIRDS KAQNVAICLS DSVELLATLF
AGAFYGFKIT IIPHNLASEE LATYLQQAKA DLLVAEAGAV DLDVVSKART SLNNVVWVTK
VGNQHLDWSQ GPDELGSQIK VAVWQDLVKD SGNSATSELP ASDPNVATPS ITTLWFPPTG
PGSFVEYTAA NLISAVGALG SSLPRNELLR DSDLFLSIDS LSHTYSLCWT LAALYANASV
ALNSVAGEVV DLALATAGIS PTVLVASSHT ISDYHAQRMG PSMGPITNIG RYFQSRSLDS
GVMPTRNWLW NLSSAAPTAG LSLDKLRLLF ISHRADGNKQ NRLTSDQLTD LRIFTGARVV
YALTAQNVAG AVCQTLPYDY RTDTGPSHFG PPTNSVEIKL IGCQENGTDE RATEGEIFVT
GPSVVSGQSS LGVKARIRDD NTITLCD
//
