ID J3KIP7_COCIM Unreviewed; 882 AA.
AC J3KIP7;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 2.
DT 13-SEP-2023, entry version 40.
DE RecName: Full=Mcm2 3 5 family protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CIMG_01213 {ECO:0000313|EMBL:EAS35859.3};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:EAS35859.3, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704911; EAS35859.3; -; Genomic_DNA.
DR RefSeq; XP_001247442.2; XM_001247441.2.
DR AlphaFoldDB; J3KIP7; -.
DR GeneID; 4565575; -.
DR KEGG; cim:CIMG_01213; -.
DR VEuPathDB; FungiDB:CIMG_01213; -.
DR InParanoid; J3KIP7; -.
DR OMA; DMSMRTW; -.
DR OrthoDB; 2682018at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 173..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 82..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..52
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 882 AA; 96543 MW; 2A17D06AF5E4DDEA CRC64;
MESPPEPSSR PTISQPDAVF SRGRNPDLSR SPYERIPSAD DTRHRRTSHS TSPERALHAN
PSSMVGLGLG SYGDAFSNVF DNGSDRRSRN QSSSSSNALH GQGRDSPDDL IHTSRNTPSE
AYLLSSYPTH LESSHTLVHN TPTSNPPGEG GRGHSGNIKC SSRKNVVQRR TSWLSISILI
LAFYSTAFSG IYLVVACVKP RYGRRVGTDG GLSPSTASLL SALFAKTIEL SFVTVFVAFL
GQVLSRRALA KRSPGISIAD MSMRSWIMQP GTLLTHWENV RYSAMTILGM AALTTAWMAM
LYTTAAETLV SPKLKFGPTE DTTLYGQVAS KFANKDYLAN KCLTPITPEM DPLEYGGTCM
QLTHVGHSYH NYQQYLADWA TISRSGNFSS RALSERPYPT GTWYDNTTVS GEWIDVQNMT
ELSRKHGRMV NIATAAMPHA GVFVASRDPR NKLRQPSDFA GFGEFYISAS VASPAIQVTC
VGMTEDELTP IVYSKWPYAQ KLNFSAWPAS APSDIPTSPD MLNETVVDDI FGFGKKGDQQ
APIFPRLPAH YNTIVNGSGR YPLHSVYLLG ASPPSETSSP YVLCSIKGGT TSKCSTQYHA
AASGGKMGVN CGDKDDELAY HRTAHKSKPF LIDPDWKNVA SNWVNSVSLG TGITDGHSSN
ARLLMQLTGG FKNETKEYSL NPRLPSLAEA LAAMGSSTLL ESTEGATFSQ YWEYGESPVI
EDGKTVYEDF PATIRVSEYA SGGTYSWQKI FYVVLVHVFL TNLVCLAYMY FDIRGTQVTD
FTEPQNIFAL ALNSPSSVRL QGACGAGPEG RQLSERWRIE MDEDDEHYYI TGKEGRERSR
NQAPGHDAAG DVEGSPQKSS LSPAVAEYRK LQKSRHSFTL LS
//
