ID J3M0A1_ORYBR Unreviewed; 999 AA.
AC J3M0A1;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=HMA domain-containing protein {ECO:0000259|PROSITE:PS50846};
GN Name=102705621 {ECO:0000313|EnsemblPlants:OB04G28260.1};
OS Oryza brachyantha (malo sina).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4533 {ECO:0000313|EnsemblPlants:OB04G28260.1};
RN [1] {ECO:0000313|EnsemblPlants:OB04G28260.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 101232 {ECO:0000313|EnsemblPlants:OB04G28260.1};
RX PubMed=23481403;
RA Chen J., Huang Q., Gao D., Wang J., Lang Y., Liu T., Li B., Bai Z.,
RA Luis Goicoechea J., Liang C., Chen C., Zhang W., Sun S., Liao Y., Zhang X.,
RA Yang L., Song C., Wang M., Shi J., Liu G., Liu J., Zhou H., Zhou W., Yu Q.,
RA An N., Chen Y., Cai Q., Wang B., Liu B., Min J., Huang Y., Wu H., Li Z.,
RA Zhang Y., Yin Y., Song W., Jiang J., Jackson S.A., Wing R.A., Wang J.,
RA Chen M.;
RT "Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying
RT Oryza genome evolution.";
RL Nat. Commun. 4:1595-1595(2013).
RN [2] {ECO:0000313|EnsemblPlants:OB04G28260.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2013) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362081}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|ARBA:ARBA00006024,
CC ECO:0000256|RuleBase:RU362081}.
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DR RefSeq; XP_006653660.1; XM_006653597.2.
DR AlphaFoldDB; J3M0A1; -.
DR STRING; 4533.J3M0A1; -.
DR EnsemblPlants; OB04G28260.1; OB04G28260.1; OB04G28260.
DR GeneID; 102705621; -.
DR Gramene; OB04G28260.1; OB04G28260.1; OB04G28260.
DR KEGG; obr:102705621; -.
DR eggNOG; KOG0207; Eukaryota.
DR HOGENOM; CLU_001771_0_2_1; -.
DR OMA; GGKFMVC; -.
DR OrthoDB; 7279at2759; -.
DR Proteomes; UP000006038; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR CDD; cd00371; HMA; 3.
DR CDD; cd02094; P-type_ATPase_Cu-like; 1.
DR Gene3D; 3.30.70.100; -; 3.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 2.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR017969; Heavy-metal-associated_CS.
DR InterPro; IPR006122; HMA_Cu_ion-bd.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 1.
DR NCBIfam; TIGR00003; copper ion binding protein; 2.
DR PANTHER; PTHR46594; P-TYPE CATION-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR46594:SF4; P-TYPE CATION-TRANSPORTING ATPASE; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 3.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00943; CUATPASE.
DR PRINTS; PR00942; CUATPASEI.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 3.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS01047; HMA_1; 2.
DR PROSITE; PS50846; HMA_2; 3.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Reference proteome {ECO:0000313|Proteomes:UP000006038};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}.
FT TRANSMEM 316..337
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 357..375
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 387..406
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 426..443
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 582..601
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 621..641
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 940..960
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 966..989
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT DOMAIN 72..138
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT DOMAIN 150..216
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT DOMAIN 225..291
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT REGION 37..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 999 AA; 107518 MW; F7D36B040B7E5010 CRC64;
MAASTRALFI SCFHGSGGGG GGGSEVSRLL VLRPRYPSMP RRPKSAAVAG EGGEGGGGDV
DLEAAAVGEE EKVAVFSVSG MTCAACAGSV EKAVKRLAGI HDAAVDVLGG RAQVVFYPAF
VSEEKIRETI EDVGFEAKLI DEEVKEKNIL VCRLHIKGMT CTSCASTVES ILQVIPGVQR
ASVALATEEA EIRYDRRIIT ASQLTDAVEE TGFEAILITT GDDQSRIDLK VDGTLDERSI
MIMKSSVEAL PGVEDIKVDP ELHKITIAYK PDQTGPRDLI EVIESAASGD LTVSIYPEAD
GRQQHRHGEI KLYKQSFLWS LVFTIPVFLT SMVFMYIPGL KDGLEKKAIN MMSIGELLRW
ILSTPVQFVI GRRFYTGAYK ALSHGSSNMD VLIALGTNTA YFYSVYSILR AASSHDYMAT
DFFETSSMLI SFILLGKYLE ILAKGKTSEA IAKLMDLAPE TATMLIYNHE GNVVGEKEID
SRLIQKNDVI KVVPGGKVAS DGFVIWGQSH VNESMITGES RPVAKRKGDT VIGGTVNENG
VLHVRATFVG SESALAQIVR LVESAQMAKA PVQKFADQIS RVFVPLVIIL SLLTWLAWFL
AGRLHGYPKS WIPPSMDSFQ LALQFGISVM VIACPCALGL ATPTAVMVAT GVGASQGVLI
KGGQALESAQ KVDCIVFDKT GTLTIGKPVV VNTRLLKNMV LREFYDCVAA AEINSEHPLA
KAVVEHAKKF HSEENHVWPE ARDFISVTGH GVKAKVNGRA VMVGNKSFML TSGIDIPVEA
LEILTEEEEK AHTAIIVAMD QEVAGIISVS DPIKPNAREV ISYLKSIKVE SIMVTGDNWG
TANAISKEVG IENTVAEAKP EQKAEKVKEL QSAGRTVAMV GDGINDSPAL VSADVGLAIG
AGTDVAIEAA DIVLMKSNLE DVITAIDLSR KTFFRIRMNY VWALGYNIIG IPIAAGVLFP
STRFRLPPWV AGAAMAASSV SVVCWSLLLR YYKSPKLGR
//
