ID J3M7E0_ORYBR Unreviewed; 710 AA.
AC J3M7E0;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Phenylalanine ammonia-lyase {ECO:0000256|RuleBase:RU003955};
DE EC=4.3.1.24 {ECO:0000256|RuleBase:RU003955};
OS Oryza brachyantha (malo sina).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4533 {ECO:0000313|EnsemblPlants:OB05G25140.1};
RN [1] {ECO:0000313|EnsemblPlants:OB05G25140.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 101232 {ECO:0000313|EnsemblPlants:OB05G25140.1};
RX PubMed=23481403;
RA Chen J., Huang Q., Gao D., Wang J., Lang Y., Liu T., Li B., Bai Z.,
RA Luis Goicoechea J., Liang C., Chen C., Zhang W., Sun S., Liao Y., Zhang X.,
RA Yang L., Song C., Wang M., Shi J., Liu G., Liu J., Zhou H., Zhou W., Yu Q.,
RA An N., Chen Y., Cai Q., Wang B., Liu B., Min J., Huang Y., Wu H., Li Z.,
RA Zhang Y., Yin Y., Song W., Jiang J., Jackson S.A., Wing R.A., Wang J.,
RA Chen M.;
RT "Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying
RT Oryza genome evolution.";
RL Nat. Commun. 4:1595-1595(2013).
RN [2] {ECO:0000313|EnsemblPlants:OB05G25140.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (APR-2013) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-phenylalanine = (E)-cinnamate + NH4(+);
CC Xref=Rhea:RHEA:21384, ChEBI:CHEBI:15669, ChEBI:CHEBI:28938,
CC ChEBI:CHEBI:58095; EC=4.3.1.24;
CC Evidence={ECO:0000256|RuleBase:RU003955};
CC -!- PATHWAY: Phenylpropanoid metabolism; trans-cinnamate biosynthesis;
CC trans-cinnamate from L-phenylalanine: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005138, ECO:0000256|RuleBase:RU003955}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU003955}.
CC -!- SIMILARITY: Belongs to the PAL/histidase family.
CC {ECO:0000256|ARBA:ARBA00007238, ECO:0000256|RuleBase:RU003954}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; J3M7E0; -.
DR STRING; 4533.J3M7E0; -.
DR EnsemblPlants; OB05G25140.1; OB05G25140.1; OB05G25140.
DR Gramene; OB05G25140.1; OB05G25140.1; OB05G25140.
DR eggNOG; KOG0222; Eukaryota.
DR HOGENOM; CLU_014801_3_0_1; -.
DR OMA; GTRRNFH; -.
DR UniPathway; UPA00713; UER00725.
DR Proteomes; UP000006038; Chromosome 5.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0045548; F:phenylalanine ammonia-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0009800; P:cinnamic acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006559; P:L-phenylalanine catabolic process; IEA:InterPro.
DR CDD; cd00332; PAL-HAL; 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR InterPro; IPR001106; Aromatic_Lyase.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR InterPro; IPR022313; Phe/His_NH3-lyase_AS.
DR InterPro; IPR005922; Phe_NH3-lyase.
DR InterPro; IPR023144; Phe_NH3-lyase_shielding_dom_sf.
DR NCBIfam; TIGR01226; phe_am_lyase; 1.
DR PANTHER; PTHR10362; HISTIDINE AMMONIA-LYASE; 1.
DR PANTHER; PTHR10362:SF34; PHENYLALANINE AMMONIA-LYASE; 1.
DR Pfam; PF00221; Lyase_aromatic; 1.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
DR PROSITE; PS00488; PAL_HISTIDASE; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|RuleBase:RU003954};
KW Phenylpropanoid metabolism {ECO:0000256|ARBA:ARBA00023051,
KW ECO:0000256|RuleBase:RU003955};
KW Reference proteome {ECO:0000313|Proteomes:UP000006038}.
SQ SEQUENCE 710 AA; 76196 MW; 7CA5446C7042622E CRC64;
MECGNGHAAA NGDGLCMAVP RADPLNWGKA AEELAGSHLD EVKRMVAEYR QPVVRIEGAS
LRIAQGAASG GAAMVELDES ARERVKASSD WVMNSMANGT DSYGVTTGFG ATSHRRTKEG
GALQRELIRF LNAGAFGTGS DGHVLPAEAT RAAMLVRINT LLQGYSGIRF EILEAVAKLL
NANVTPCLPL RGTITASGDL VPLSYIAGLV TGRENSVAVA PDGRKVNAAE AFKIAGIQGG
FFELQPKEGL AMVNGTAVGS GLASTVLFEA NVLAILAEVL SAVFCEVMNG KPEYTDHLTH
KLKHHPGQIE AAAIMEHILE GSSYMKEAKR LGELDPLMKP KQDRYALRTS PQWLGPQIEV
IRAATKSIER EINSVNDNPL IDVSRGKALP GGNFQGTPIG VSMDNTRLAI AAIGKLMFAQ
FSELVNDFYN NGLPSNLSGG RNPSLDYGFK GAEIAMASYC SELQFLGNPV TNHVQSAEQH
NQDVNSLGLI SSRKTAEAID ILKLMSSTFL VALCQAIDLR HIEENVKAAV KTCVMTVAKK
TLSTNSTGGL HVARFCEKDL LKEIDREAVF AYADDPCSAN YPLMKKLRNV LVERALANGA
AEFNADTSVF AKVAQFEEEL RTALPRAVEA ARAAVESGTA ATPNRITECR SYPLYRFVRE
ELGTAYLTGE KTRSPGEELN KVLVAINQGK HIDPLLECLE EWNGAPLPIC
//
