ID J3S435_CROAD Unreviewed; 546 AA.
AC J3S435;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 22-FEB-2023, entry version 29.
DE SubName: Full=CAP-GLY domain containing linker protein family, member 4 {ECO:0000313|EMBL:AFJ49602.1};
OS Crotalus adamanteus (Eastern diamondback rattlesnake).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus.
OX NCBI_TaxID=8729 {ECO:0000313|EMBL:AFJ49602.1};
RN [1] {ECO:0000313|EMBL:AFJ49602.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Venom gland {ECO:0000313|EMBL:AFJ49602.1};
RX PubMed=23025625; DOI=10.1186/1471-2164-13-312;
RA Rokyta D.R., Lemmon A.R., Margres M.J., Aronow K.;
RT "The venom-gland transcriptome of the eastern diamondback rattlesnake
RT (Crotalus adamanteus).";
RL BMC Genomics 13:312-312(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JU174076; AFJ49602.1; -; mRNA.
DR AlphaFoldDB; J3S435; -.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR PANTHER; PTHR18916:SF32; CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 4; 1.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01302; CAP_GLY; 2.
DR SMART; SM00248; ANK; 3.
DR SMART; SM01052; CAP_GLY; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 2.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 2.
PE 2: Evidence at transcript level;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT REPEAT 186..218
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 303..345
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT DOMAIN 498..540
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 440..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 546 AA; 59521 MW; 0F5F4C2CC3ACDAED CRC64;
MTIEDLPDPS EEGVSLSRRH QFFISGSEDS ITHSVSAAPM PSEYEFSFFD PNDAACREIL
FNPKTSVSEL FAILRQWVPQ VQQNIDVIGN EIIKRGCNVN DRDDLTDMTL LHYTCKSGAH
GIGDVKTAAK FASQLIELGA DISSRSRWTN MNALHYAAYF DVPELISIIL KNAKPKDIDA
TCSDFDFGTA LHIAAFNLCT GAVKRLLEHG ANPAFRNDKG QTPADVVPDP VDMPLEMADA
AASAKEIKQM LLDAVPLVCD LSNIMLPNYD NVTGKDMLEL LGLKLGDRVV IAGQKVGTLR
FCGMTEFASG QWAGIELDEP DGKNNGTVGR VQYFKCTPKH GIFAPLSKIS KISGHKKSTK
ASSSRPLPII KSKKIDVTHI NSKVNSGLSR KDSTSNSTFV SSEEVKKTVS GKQANYLGSS
SSSSSTVSLD SKLNCPKKCN STSNKENMKD HPISSKSMAE GNNTFLSAKK IAFEEGEIQI
GERVLVVGQR TGIVRFYGTT KFAPGLWYGI ELDKPRGKND GSVAGIQYFR CPPRYGVFAP
PSRVQK
//
