ID   J3S8B0_CROAD            Unreviewed;       783 AA.
AC   J3S8B0;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Nuclear cap-binding protein subunit 1 {ECO:0000313|EMBL:AFJ49603.1, ECO:0000313|EMBL:JAI12277.1};
OS   Crotalus adamanteus (Eastern diamondback rattlesnake).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus.
OX   NCBI_TaxID=8729 {ECO:0000313|EMBL:AFJ49603.1};
RN   [1] {ECO:0000313|EMBL:AFJ49603.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Venom gland {ECO:0000313|EMBL:AFJ49603.1};
RX   PubMed=23025625; DOI=10.1186/1471-2164-13-312;
RA   Rokyta D.R., Lemmon A.R., Margres M.J., Aronow K.;
RT   "The venom-gland transcriptome of the eastern diamondback rattlesnake
RT   (Crotalus adamanteus).";
RL   BMC Genomics 13:312-312(2012).
RN   [2] {ECO:0000313|EMBL:JAI12277.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Margres M.J., Wray K.P., McGivern J.J., Seavy M., Sanader D., Facente J.,
RA   Rokyta D.R.;
RT   "The extremes of toxin expression variation revealed in two sympatric snake
RT   species.";
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the NCBP1 family.
CC       {ECO:0000256|ARBA:ARBA00007413}.
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DR   EMBL; JU174077; AFJ49603.1; -; mRNA.
DR   EMBL; GBEX01002283; JAI12277.1; -; mRNA.
DR   AlphaFoldDB; J3S8B0; -.
DR   GO; GO:0005846; C:nuclear cap binding complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000339; F:RNA cap binding; IEA:InterPro.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; IEA:UniProtKB-KW.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.180; -; 3.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027159; CBP80.
DR   InterPro; IPR015172; MIF4G-like_typ-1.
DR   InterPro; IPR015174; MIF4G-like_typ-2.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   PANTHER; PTHR12412; CAP BINDING PROTEIN; 1.
DR   PANTHER; PTHR12412:SF2; NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1; 1.
DR   Pfam; PF02854; MIF4G; 1.
DR   Pfam; PF09088; MIF4G_like; 1.
DR   Pfam; PF09090; MIF4G_like_2; 1.
DR   SMART; SM00543; MIF4G; 1.
DR   SUPFAM; SSF48371; ARM repeat; 3.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   mRNA capping {ECO:0000256|ARBA:ARBA00023042};
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW   mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW   Nonsense-mediated mRNA decay {ECO:0000256|ARBA:ARBA00023161};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transport {ECO:0000256|ARBA:ARBA00022816}.
FT   DOMAIN          23..235
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   COILED          640..705
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   783 AA;  91830 MW;  8A80919A361F3F39 CRC64;
     MSRRRHRDEN DEQPYKKRKV SIAERLESLI SKVGEKSPFS LESRIEGLAG VLEADLPNYK
     SKILKLLCTV ARLLPQKMTI YTTLVGLLNA RNYNFGGEFV EAMIRQLKEC LKANLYNEAI
     YLVRFFSDLV NCHVIAAPSM VAMFENFVNV TQEEDVPQVR CDWYVYAFLS SLPWVGKELY
     EKKDTEMEQI LSTVENYLKR RQKNHVPMLQ VWSADKPHPQ EEYLDCLWAQ IQKMKKDHWQ
     ERHIPRPYLA FDSVLCEALQ HNLPPFTPPP HTADSVYPMP RVTFRMFDYT DDPEGPVMPG
     SHSVERFVIE ENLHCIIRSF WKERKTCASQ LTSYPGNNKI PLNYHIVEVI FAELFQLPIP
     PHTEIMYTTL FIELCKLQPG SLPQVLAQAT EMLYMRLDTM NTICIDRFMN WFSHHLSNFE
     FRWSWEDWSD SVSEVLDRPK PKFVREVLEK CMRLSYHQRI IDIVPASFSV LTPANPACIY
     KYGDESNKSL PGYNVALCVS IAIKNKASND EIFAILKDVP NLNQDDDDDE GFSFNPLKIE
     VFVQALLHLA SKSFSHSFSA LGKFREVLRT LAESDEGKLH ILRVMYEVWK NHSQMIAVLV
     DKMIRTQIVD CAAVANWIFS PELSHDFTRF YIWEILHSTI RKMNKHVMMI QKELEEAKEK
     LAKQQKRRDD SRRNERESWP LEEQIERLQE KVESAQSEQK NLFLVIFQRF IMILTEHLVR
     CETGGIDVIT PWYRNCIERL QQIFLQHHQI IQQYMVTLEN LLFTAELDYH ILAIFQQFCA
     LQG
//