ID   J3SFC0_CROAD            Unreviewed;       536 AA.
AC   J3SFC0;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=L-amino-acid oxidase {ECO:0000256|ARBA:ARBA00012806};
DE            EC=1.4.3.2 {ECO:0000256|ARBA:ARBA00012806};
OS   Crotalus adamanteus (Eastern diamondback rattlesnake).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus.
OX   NCBI_TaxID=8729 {ECO:0000313|EMBL:AFJ51511.1};
RN   [1] {ECO:0000313|EMBL:AFJ51511.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Venom gland {ECO:0000313|EMBL:AFJ51511.1};
RX   PubMed=23025625; DOI=10.1186/1471-2164-13-312;
RA   Rokyta D.R., Lemmon A.R., Margres M.J., Aronow K.;
RT   "The venom-gland transcriptome of the eastern diamondback rattlesnake
RT   (Crotalus adamanteus).";
RL   BMC Genomics 13:312-312(2012).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the flavin monoamine oxidase family. FIG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00005465}.
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DR   EMBL; JU175987; AFJ51511.1; -; mRNA.
DR   AlphaFoldDB; J3SFC0; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0001716; F:L-amino-acid oxidase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.90.660.10; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR   PANTHER; PTHR10742:SF416; SPERMINE OXIDASE; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          34..524
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   536 AA;  60239 MW;  71395E831F1C7B00 CRC64;
     MQSGDTSEES TDDPLSSRPR GARQPRIVVI GAGLAGLSAA KTLLANGFTD VTVLEASDRI
     GGRVQSVRLA NATFELGATW IHGSNGNPVY HLAEDNGLLE ETTDDERSVG RISLYSRNGV
     AYHLTSSGQR IPKDVVEEFS DLYNEVYNLT QEFFQNGKPV NADSQNSVGI FTRDVVRKRI
     KADPDESETV KKLKLAMIQQ YLKQVESCES SSHSMDEVSL SEFGEWTEIP GAHHIIPCGF
     MKIVEILSRS IPESVIHLNK PVKCIHWNQS ISKEIEQVAD HNEDRLEDNA GYSVLLECED
     CEFILADHVI VTVSLGVLKK RHEDMFYPPL PDEKVLAIQK LGISTTDKIF LEFEAPFWSP
     ECNSFQFVWE DEDEAESLTY PEELWYKKIC SFDVLYPPER YGHVLSGWIC GEEALIMEKY
     DDETVAEICT EMLRKFTGNP DIPKPRRILR SSWGSNPYIR GSYSYTQVGS SGADVEKLAK
     PLPYTESSKT VPLQVMFSGE ATHRKYYSTT HGALLSGQRE ATRLTEMYQD LLSCKN
//