ID J4GT57_9APHY Unreviewed; 1235 AA.
AC J4GT57;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=PhoX domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=FIBRA_06650 {ECO:0000313|EMBL:CCM04470.1};
OS Fibroporia radiculosa.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Fibroporiaceae; Fibroporia.
OX NCBI_TaxID=599839 {ECO:0000313|EMBL:CCM04470.1, ECO:0000313|Proteomes:UP000006352};
RN [1] {ECO:0000313|EMBL:CCM04470.1, ECO:0000313|Proteomes:UP000006352}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TFFH 294 {ECO:0000313|EMBL:CCM04470.1,
RC ECO:0000313|Proteomes:UP000006352};
RX PubMed=22247176; DOI=10.1128/AEM.06745-11;
RA Tang J.D., Perkins A.D., Sonstegard T.S., Schroeder S.G., Burgess S.C.,
RA Diehl S.V.;
RT "Short-read sequencing for genomic analysis of the brown rot fungus
RT Fibroporia radiculosa.";
RL Appl. Environ. Microbiol. 78:2272-2281(2012).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; HE797157; CCM04470.1; -; Genomic_DNA.
DR RefSeq; XP_012183753.1; XM_012328363.1.
DR AlphaFoldDB; J4GT57; -.
DR STRING; 599839.J4GT57; -.
DR GeneID; 24099381; -.
DR HOGENOM; CLU_002131_1_0_1; -.
DR InParanoid; J4GT57; -.
DR OrthoDB; 5392990at2759; -.
DR Proteomes; UP000006352; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06876; PX_MDM1p; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006352};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 108..301
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 438..519
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 862..980
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 595..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1235 AA; 137704 MW; 8D2A83EAECD1433D CRC64;
MVVSSKHTAI FIALFAALLP LTVRVASSPL ALVLLLPVLT VFTVFGFLLL NIALGYALDS
TRPASQNTLP YAARPLAFST PAAWQAVLTR SQWSHKAPQT LPQLYPESPA TSAALNDILI
MIVRDFVLVW YKEISSSPSF PTAVSSVLHS SLEQLLIRAT TLDIPALIAR RIVPKVTAHI
DQFRQSEVAL RGAGLERRLT QSEELDLLLA SRYAGRGDGK LHRAVDNLSS TFTKQTEEHH
LRELVDKALP LILPEKDAKS EAVRIVVKEL VACSILYPIM EMLADPDFWN RSIDLVAGAA
IRQQRLVSKV RNILEAQLPR SQVRTTEPRS STTEKITIRT DPRQFESFLR SISRCSSLLD
ARRLKNDVMS EIRRTRVLLA NHEKDDWING EKTEDIVAFL DRLYTAKRKA EKRIVVLGGE
ADPRQPTYSE APSTSRISLR DVLTNPSSLS YYMEFMDRRH RSLLVQFWLT VESFKNPLES
VDSGSSDEDD EAVLDPARSA TLKEDISMMK DLYFSGSTPD PVLASVSQKH VNAIKTFGLD
ERIPTLVAER RVRRSVMLAQ RQVEKDMEQD FEDFQRSELW FHVVGDIEAT GRTRSAVLGP
GRDDDPMSIS RTSSGTSASM STSVQHGAFH VPRSSSTPIL NLPPQSRTFR LDESLPITPV
INPLPRASTS NLELLMSPIP ASPSMSTSRA PLFDDPEDAK MTEQSRRMDA IQAALTDIIA
LDGHDNARGR VSTTTGETTE LTESMVEERA RGAVFDDVDE EDDGQEERDD DIQKEHGSFQ
LAGPGDLQLS HEIMRLASKV DALHSQSAML DTLIKKAELT GDTQELKLLR KSRSSLAREL
RELNFQKSQY EQQESANRLV SDRTKVAIVN SAVGEEDGKS VVRYLVEVQQ LAHDGLFSSG
WVVARRYNEF FTMHNKLRER YSFVRNLDFP GKRLVTALSA SFVDSRKAAL EKYLQSLITI
PAVCESDELR MFLSRDSPFI AAESLNPSTA APAPSSSKGI VRTVYQSVAE SIDDMFFGPS
MLDVIIQRLT TQAAEFAGIV GSGIHDEDLV AQVLKASGKT SSDDTLLQLP GDLKPLQGET
SSSSFSSPIC DLVLAVFELD KKNNWLRRQA IVIILQQVFG DTIERKLRET FKSYMDESHI
MSYINIFRDS LWPGGKLKPP GAPRTTEEKL RAKDEANRKL SALMPDLVAN MIGRSNARRG
ARRIFAVLQN RRLNQHLLYT IVDEVFAALF PPSSS
//
